38197-43-2

Basic information

• Product Name: 2-BroMo-1-Methoxy-3-Methylbenzene
• Synonyms: Benzene, 2-broMo-1-Methoxy-3-Methyl-;2-Bromo-3-methoxytoluene
• CAS NO: 38197-43-2
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.06046
• Mol File: 38197-43-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 35.5-36.5 °C
• Boiling Point: 110-115 °C(Press: 16 Torr)
• Appearance: /
• Density: 1.378±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BroMo-1-Methoxy-3-Methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-1-Methoxy-3-Methylbenzene(38197-43-2)
• EPA Substance Registry System: 2-BroMo-1-Methoxy-3-Methylbenzene(38197-43-2)

Safety Data

• Hazardous Substances Data: 38197-43-2(Hazardous Substances Data)

Usage

General Description

2-Bromo-1-methoxy-3-methylbenzene, also referred to as 5-bromo-2-methylanisole, is a synthetic organic compound. As a derivative of anisole, it belongs to the class of aromatic compounds known as benzene and its derivatives. This chemical is identified with the CAS Registry Number 6071-25-6. In its pure form, it appears as a granular, crystalline powder or solid. It’s primarily used in the field of organic synthesis. As with many complex organic compounds, adequate safety measures should be taken in its handling and storage as the compound can be potentially hazardous.

Upstream product

• 22061-78-5 2-bromo-3-methylphenol 
• 77-78-1 dimethyl sulfate 
• 50868-73-0 2-methoxy-6-methylbenzeneamine 
• 5345-42-6 1-methoxy-3-methyl-2-nitro-benzene 
• 108-39-4 3-methyl-phenol 
• 4920-77-8 3-methyl-2-nitrophenol 
• 74-88-4 methyl iodide 

Downstream Products

• 100-84-5 1-methoxy-3-methyl-benzene 
• 10401-18-0 2-bromo-3-methoxybenzaldehyde 
• 6161-65-5 2-methoxy-6-methyl-benzoic acid 
• 1200-95-9 2'-Hydroxy-6'-methylbutyrophenon 
• 22061-78-5 2-bromo-3-methylphenol 
• 25181-65-1 2-(2-bromo-3-methylphenoxy)acetic acid 
• 140111-59-7 2-(6-methoxy-2-methylphenyl)ethanol 
• 104178-99-6 6-Methoxy-2-methyl-benzyldimethylamin; 3-Methoxy-2-dimethylaminomethyl-toluol 

Relevant articles and documents

Studies toward the Total Syntheses of Calyciphylline D-Type Daphniphyllum Alkaloids

An efficient construction of an aza-[5.7.6.5] tetracyclic core structure of calyciphylline D-type Daphniphyllum alkaloids has been achieved. The synthetic route features a diastereoselective cyclopropanation, efficient construction of the core bridged 8-aza-[3.2.1]octane skeleton through a [3 + 2] IMCC strategy, oxidative dearomatization of phenol, and gram-scale preparation in each step.

ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7)

Disclosed are small molecule antagonists of α4β7 integrin, and methods of using them to treat a number of specific diseases or conditions.

1,2-asymmetric induction in diastereoselective zwitterionic aza-Claisen rearrangements: Key steps in optically active alkaloid synthesis

The zwitterionic aza-Claisen rearrangement of optically active N-allylpyrrolidines and α-phenoxyacetyl fluorides proceeds with complete simple diastereoselectivity (internal asymmetric induction) and complete 1,2-asymmetric induction to generate a new C-C bond adjacent to a chiral C-N-Boc functionality. The resulting γ,δ-unsaturated amides were cyclised to give the corresponding pyrrolizidinones, which enabled the determination of the relative configuration of the stereotriads. Vinyl group degradation and a final lactam reduction gave an optically active analogue of (+)-petasinine (a pyrrolizidine alkaloid). Furthermore, the stereotriad-containing amides should be useful key intermediates for the total synthesis of optically active elaeocarpin (an indolizidine alkaloid). Copyright