1369967-05-4Relevant articles and documents
INHIBITORS OF HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE 1
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Page/Page column 44, (2012/11/13)
Disclosed are inhibitors of human APE1, for example, of formula (I), wherein A, B, X, R2, and R3 are as defined herein, that are useful in treating an APE1 mediated disease or disorder, e.g., cancer. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the invention, a method of treating cancer in a mammal and a method of potentiating treatment of cancer.