1369998-46-8

Basic information

• Product Name: (1S,2R)-(-)-1-phenyl-1-(N,N-diethylamino)-2-(tosylamino)propane
• Synonyms: (1S,2R)-(-)-1-phenyl-1-(N,N-diethylamino)-2-(tosylamino)propane
• CAS NO: 1369998-46-8
• Molecular Weight: 360.521
• Mol File: 1369998-46-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2R)-(-)-1-phenyl-1-(N,N-diethylamino)-2-(tosylamino)propane(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-(-)-1-phenyl-1-(N,N-diethylamino)-2-(tosylamino)propane(1369998-46-8)
• EPA Substance Registry System: (1S,2R)-(-)-1-phenyl-1-(N,N-diethylamino)-2-(tosylamino)propane(1369998-46-8)

Safety Data

• Hazardous Substances Data: 1369998-46-8(Hazardous Substances Data)

Upstream product

• 1369998-47-9 (1R,2R)-1-phenyl-2-(1-piperidinyl)-1-chloropropane hydrochloride 
• 58107-41-8 N-[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-4-methylbenzenesulfonamide 
• 40626-29-7 Acutrim 
• 109-89-7 diethylamine 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Remarkable enantioselective α-amination in 1-phenyl-2-(N-alkylamino)- 1-propanol

(1R,2R)-1-Phenyl-1-alkyl/arylamino-2-(N-alkylamino)propane hydrochloride salts have been synthesized with high degree of enantiomeric purity from (1S,2R)-(+)-1-phenyl-2-(N-alkylamino)-1-propanol through the corresponding chloro derivatives. This reaction sequence involves three inversions with overall inversion of configuration at C-1. Copyright