1369999-74-5Relevant academic research and scientific papers
Synthesis of allyl acetates via palladium-catalysed functionalisation of allenes and 1,3-dienes
Husinec, Suren,Petkovic, Milos,Savic, Vladimir,Simic, Milena
experimental part, p. 399 - 408 (2012/03/11)
-Allylpalladium intermediates are known to participate efficiently in transformations involving nucleophilic species. Exploring these processes, we have developed a method for the preparation of allyl acetates via palladium-catalysed functionalisation of
Palladium-catalysed synthesis of allyl acetates from allenes
Husinec, Suren,Jadranin, Milka,Markovic, Rade,Petkovic, Milos,Savic, Vladimir,Todorovic, Nina
scheme or table, p. 4066 - 4068 (2010/08/07)
Allyl acetates were synthesised from allenes utilising methodology based on the general reactivity of π-allyl palladium intermediates which participate efficiently in transformations involving nucleophiles. Reactions of allenes and aryl iodides in the presence of AcONa and Pd(OAc)2/PPh3 as the catalytic system afforded allyl acetates in moderate to good yields. Monosubstituted allenes, depending on their structure, produced either a separable mixture of two regioisomeric products or a single regioisomer. As allylic acetates can be easily hydrolysed, the methodology is applicable for the synthesis of allyl alcohols as well.
