13700-08-8 Usage
Description
2-Hydroxyethyl Methanethiosulfonate, also known as MESNA, is a chemical compound that is a yellow oil with a slightly cloudy appearance. It is known for its specific and rapid reaction with thiols to form mixed disulfides, making it a valuable tool in various applications.
Uses
Used in Pharmaceutical Research:
2-Hydroxyethyl Methanethiosulfonate is used as a probe for studying the structures of various receptor channels, such as the ACh receptor channel, the GABA receptor channel, and lactose permease. Its ability to form mixed disulfides with thiols allows researchers to investigate the structural and functional aspects of these channels, contributing to a better understanding of their roles in cellular processes and potential therapeutic applications.
Used in Chemical Synthesis:
2-Hydroxyethyl Methanethiosulfonate is used as a reagent in the synthesis of various organic compounds, particularly those involving thiol groups. Its specificity and rapid reaction with thiols make it a valuable tool for chemists working on the development of new drugs and other chemical products.
Used in Analytical Chemistry:
2-Hydroxyethyl Methanethiosulfonate is used as an analytical tool for the detection and quantification of thiols in various samples. Its ability to form mixed disulfides with thiols allows for the selective and sensitive detection of these compounds, which are important in various biological and environmental processes.
Check Digit Verification of cas no
The CAS Registry Mumber 13700-08-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,0 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13700-08:
(7*1)+(6*3)+(5*7)+(4*0)+(3*0)+(2*0)+(1*8)=68
68 % 10 = 8
So 13700-08-8 is a valid CAS Registry Number.
InChI:InChI=1/C3H8O3S2/c1-8(5,6)7-3-2-4/h4H,2-3H2,1H3
13700-08-8Relevant articles and documents
PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS
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Page/Page column 4; 5, (2010/07/08)
The present invention relates to new prostaglandin derivatives having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of glaucoma and ocular hypertension.
5-Fluorouracil derivatives and their use for the treatment of cancer
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Page/Page column 6, (2008/12/06)
The present invention relates to 5-fluoropyrimidine compounds of formula I that are useful for preventing, treating or reducing tumoral diseases and pathological conditions involving various cancer forms.
Anti-inflammatory agents
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Page/Page column 3-4, (2008/06/13)
The present invention relates to novel thiosulfonates derivatives. The present invention also provides methods for preventing, treating and/or reducing inflammation-associated diseases in the cardiovascular, connective tissue, pulmonary, gastrointestinal, respiratory, urogenital, nervous or cutaneous systems as well as infective and tumoral diseases employing said compounds.
