13700-08-8

Usage

Uses

Used in Pharmaceutical Research:
2-Hydroxyethyl Methanethiosulfonate is used as a probe for studying the structures of various receptor channels, such as the ACh receptor channel, the GABA receptor channel, and lactose permease. Its ability to form mixed disulfides with thiols allows researchers to investigate the structural and functional aspects of these channels, contributing to a better understanding of their roles in cellular processes and potential therapeutic applications.
Used in Chemical Synthesis:
2-Hydroxyethyl Methanethiosulfonate is used as a reagent in the synthesis of various organic compounds, particularly those involving thiol groups. Its specificity and rapid reaction with thiols make it a valuable tool for chemists working on the development of new drugs and other chemical products.
Used in Analytical Chemistry:
2-Hydroxyethyl Methanethiosulfonate is used as an analytical tool for the detection and quantification of thiols in various samples. Its ability to form mixed disulfides with thiols allows for the selective and sensitive detection of these compounds, which are important in various biological and environmental processes.

InChI:InChI=1/C3H8O3S2/c1-8(5,6)7-3-2-4/h4H,2-3H2,1H3

Upstream product

• 1950-85-2 sodium methanethiosulfonate 
• 540-51-2 2-bromoethanol 
• 6340-98-3 potassium methanethiosulphonate 

Downstream Products

• 38254-63-6 S-(2-hydroxyethylmercapto)-L-cysteine 
• 1070174-99-0 2-butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl]-1H-imidazole-5-carboxylic acid 2-(methylsulfonylthio)ethyl ester 
• 2387-23-7 1,3-Dicyclohexylurea 
• 948028-89-5 [2-(2,6-dichloro-phenylamino)phenyl]acetic acid 2-methanesulfonylsulfanyl-ethyl ester 
• 212207-24-4 benzocaine methanethiosulfonate 
• 917471-50-2 (Z)-5-fluoro-2-methyl-1-[[4-(methylsulfone)phenyl]methylene]-1H-indene-3-acetic acid 2-methanesulfonylsulfanylethyl ester 

Relevant academic research and scientific papers

PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS

The present invention relates to new prostaglandin derivatives having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of glaucoma and ocular hypertension.

Cardiovascular agents

The present invention relates to novel compounds that are derivatives of angiotensin receptor blocker (ARB) that comprise in their formula a polysulfurated group and that are useful for treating cardio-vascular diseases, such as hypertension, ischemic heart disease, atherosclerosis, metabolic syndrome, etc. also in combination with other cardiovascular agents.

5-Fluorouracil derivatives and their use for the treatment of cancer

The present invention relates to 5-fluoropyrimidine compounds of formula I that are useful for preventing, treating or reducing tumoral diseases and pathological conditions involving various cancer forms.

PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS

The present invention relates to new prostaglandin derivatives having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of glaucoma and ocular hypertension.

Anti-inflammatory agents

The present invention relates to novel thiosulfonates derivatives. The present invention also provides methods for preventing, treating and/or reducing inflammation-associated diseases in the cardiovascular, connective tissue, pulmonary, gastrointestinal, respiratory, urogenital, nervous or cutaneous systems as well as infective and tumoral diseases employing said compounds.

SULINDAC DERIVATIVES FOR TREATMENT OF CANCER

The present invention relates to novel non steroidal anti-inflammatory compounds (NSAIDs) derivatives of sulindac, for the treatment/prevention, alone or in combination, of cancer.