1370031-72-3Relevant academic research and scientific papers
Pd-catalyzed and CsF-promoted reaction of bromoalkynes with isocyanides: Regioselective synthesis of substituted 5-iminopyrrolones
Li, Yibiao,Zhao, Jian,Chen, Huoji,Liu, Bifu,Jiang, Huanfeng
, p. 3545 - 3547 (2012/06/01)
The palladium-catalyzed and CsF-promoted annulation reaction of bromoalkynes and isocyanides regioselectively affords a diverse set of 5-iminopyrrolone derivatives. This chemistry presumably proceeds through the bromoacrylamide intermediates, which can be readily prepared from the nucleophilic addition reaction of isocyanides to bromoalkynes in the presence of CsF.
