137017-16-4Relevant academic research and scientific papers
Novel bridgehead nitrogen heterocycles: Synthesis and antimicrobial activity of 2H-imidazopyrazolothiazoles
Mohan, Jag,Kiran
, p. 898 - 900 (2007/10/02)
Synthesis of 3-substituted 3,3a,6,7-tetrahydro-2H-imidazopyrazolothiazoles (IIIa) and their 2-phenyl derivatives (IIIb) have been achieved in a single step by treating 2-arylidene-5,6-dihydroimidazothiazolidin-3-ones (II) with hydrazine and phenylhydrazine, respectively.Compounds II in turn have been obtained by condensing 2-mercaptoimidazoline with ethyl chloroacetate and aldehydes in the presence of pyridine and piperidine.Compounds III constitute a novel and hitherto unknown heterocyclic system.The antibacterial and antifungal activities of IIIa and IIIb have also been determined.
