1370263-13-0Relevant academic research and scientific papers
Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity
Dos Santos, Edson Dos A.,Hamel, Ernest,Bai, Ruoli,Burnett, James C.,Tozatti, Camila Santos Suniga,Bogo, Danielle,Perdomo, Renata T.,Antunes, Alexandra M.M.,Marques, M. Matilde,Matos, Maria De F.C.,De Lima, Dênis P.
, p. 4669 - 4673 (2013)
We have devised a procedure for the synthesis of analogs of combretastatin A-4 (CA-4) containing sulfur and selenium atoms as spacer groups between the aromatic rings. CA-4 is well known for its potent activity as an inhibitor of tubulin polymerization, a
