52692-09-8

Basic information

• Product Name: 4-Iodo-2-nitroanisole
• Synonyms: 4-IODO-2-NITROANISOLE;4-iodo-1-methoxy-2-nitrobenzene
• CAS NO: 52692-09-8
• Molecular Formula: C₇H₆INO₃
• Molecular Weight: 279.03
• Mol File: 52692-09-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 96-98°C
• Boiling Point: 330.8 °C at 760 mmHg
• Flash Point: 153.9 °C
• Appearance: /
• Density: 1.893g/cm³
• Vapor Pressure: 0.000313mmHg at 25°C
• Refractive Index: 1.629
• Sensitive: Light Sensitive
• CAS DataBase Reference: 4-Iodo-2-nitroanisole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Iodo-2-nitroanisole(52692-09-8)
• EPA Substance Registry System: 4-Iodo-2-nitroanisole(52692-09-8)

Safety Data

• Statements: 23/24/25
• Safety Statements: 36/37-45
• Hazardous Substances Data: 52692-09-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6INO3/c1-12-7-3-2-5(8)4-6(7)9(10)11/h2-4H,1H3

Upstream product

• 696-62-8 para-iodoanisole 
• 577-72-0 4-methoxy-3-nitroaniline 
• 364-75-0 1-fluoro-4-iodo-2-nitro-benzene 
• 124-41-4 sodium methylate 
• 186581-53-3 diazomethane 
• 21784-73-6 4-iodo-2-nitrophenol 
• 352-34-1 4-fluoro-1-iodobenzene 
• 4920-80-3 3-methoxy-2-nitrobenzoic acid 
• 364-76-1 4-Fluoro-3-nitroaniline 
• 7697-37-2 nitric acid 
• 91-23-6 2-Nitroanisole 

Downstream Products

• 119-27-7 2,4-dinitroanisole 
• 77770-09-3 3-amino-4-methyloxyphenyliodide 
• 851218-51-4 ethyl 3-(4-methoxy-3-nitrophenyl)propynoate 
• 28896-47-1 2,4-diiodoanisole 
• 5399-03-1 2-iodo-1-methoxy-4-nitrobenzene 
• 1242653-18-4 5-(cyclohexylidene(4-methoxy-3-nitrophenyl)methyl)-1,2,3-trimethoxybenzene 
• 1242653-21-9 5-(cyclopentylidene(4-methoxy-3-nitrophenyl)methyl)-1,2,3-trimethoxybenzene 
• 1242653-31-1 1,2,3-trimethoxy-5-(1-(4-methoxy-3-nitrophenyl)-2-methylprop-1-en-1-yl)benzene 
• 1070195-65-1 1-(4'-methoxy-3'-nitrophenyl)-1-(3'',4'',5''-trimethoxyphenyl)ethylene 
• 1334752-47-4 2-methoxy-5-(4,5,6-trimethoxy-indol-1-yl)-phenylamine 
• 1369813-84-2 3-(N-methylamino)-4-methyloxyphenyl iodide 
• 1388628-73-6 3-(N-tert-butyloxycarbonyl-N-methylamino)-4-methyloxyphenyl iodide 
• 1416991-31-5 (Z)-1-methoxy-4-(2-methoxy-1-(3,4,5-trimethoxyphenyl)-vinyl)-2-nitrobenzene 
• 1416991-21-3 C₁₉H₂₁NO₇ 

Relevant articles and documents

Method for synthesizing m-iodonitrobenzene compound

Provided is a method for synthesizing m-iodonitrobenzene; in the presence of oxygen gas, a palladium catalyst, a copper additive, a bismuth reagent and potassium phosphate, an o-nitrobenzoic acid compound and metal iodide are subjected to a substitution reaction in an organic solvent to form a corresponding m-iodonitrobenzene compound, wherein a metal in the metal iodide is an alkali metal or an alkaline earth metal. The method has obvious advantages of cheap and easily obtained reaction raw materials (including o-nitrobenzoic acid and MI), small amount of the metal catalyst, minimum environmental pollution with oxygen gas as an oxidant, good tolerance on various functional groups on an aromatic ring and the like. The method can be widely applied in the fields of synthesis of drugs, materials, natural products and the like in industrial and academic circles.

Gold(I)-catalyzed iodination of arenes

A wide variety of electron-rich arenes were efficiently converted into the corresponding iodinated compounds via a gold(I)-catalyzed reaction under mild conditions. Georg Thieme Verlag Stuttgart. New York.