1370287-43-6 Usage
General Description
3-Bromo-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester is a chemical compound with the molecular formula C10H10BrN3O2. It is an ethyl ester derivative of 3-bromo-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid, belonging to the pyrazolopyrimidine class of compounds. This chemical is used in pharmaceutical and research applications, particularly in the development of new drugs and biologically active molecules. It may also have potential use in medicinal chemistry and as a building block for the synthesis of more complex compounds. Its specific properties and potential uses are of interest to scientists and researchers in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1370287-43-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,0,2,8 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1370287-43:
(9*1)+(8*3)+(7*7)+(6*0)+(5*2)+(4*8)+(3*7)+(2*4)+(1*3)=156
156 % 10 = 6
So 1370287-43-6 is a valid CAS Registry Number.
1370287-43-6Relevant articles and documents
Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A)
Blad, Clara C.,Van Veldhoven, Jacobus P. D.,Klopman, Corné,Wolfram, Dieter R.,Brussee, Johannes,Lane, J. Robert,Ijzerman, Adriaan P.
supporting information; experimental part, p. 3563 - 3567 (2012/06/04)
A number of pyrazolopyrimidines were synthesized and tested for their positive allosteric modulation of the HCA2 receptor (GPR109A). Compound 24, an efficacious and potent agonist and allosteric enhancer of nicotinic acid's action, was the basis for most other compounds. Interestingly, some of the compounds were found to increase the efficacy of the endogenous ligand 3-hydroxybutyrate and enhance its potency almost 10-fold. This suggests that the pyrazolopyrimidines may have therapeutic value when given alone.
