1370287-60-7

Basic information

• Product Name: 7-ethyl-3-(4-isopropylphenyl)-N-(2-phenoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide
• Synonyms: 7-ethyl-3-(4-isopropylphenyl)-N-(2-phenoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide
• CAS NO: 1370287-60-7
• Molecular Weight: 428.534
• Mol File: 1370287-60-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-ethyl-3-(4-isopropylphenyl)-N-(2-phenoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 7-ethyl-3-(4-isopropylphenyl)-N-(2-phenoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide(1370287-60-7)
• EPA Substance Registry System: 7-ethyl-3-(4-isopropylphenyl)-N-(2-phenoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide(1370287-60-7)

Safety Data

• Hazardous Substances Data: 1370287-60-7(Hazardous Substances Data)

Upstream product

• 4949-44-4 ethyl propanoylacetate 
• 16475-76-6 ethyl 2-(ethoxymethylene)-3-oxopentanoate 
• 1370287-41-4 ethyl 7-ethyl-3-(4-isopropylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate 
• 1370287-45-8 7-ethyl-3-(4-isopropylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid 
• 1758-46-9 2-phenoxyethanamine 

Relevant articles and documents

Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A)

A number of pyrazolopyrimidines were synthesized and tested for their positive allosteric modulation of the HCA2 receptor (GPR109A). Compound 24, an efficacious and potent agonist and allosteric enhancer of nicotinic acid's action, was the basis for most other compounds. Interestingly, some of the compounds were found to increase the efficacy of the endogenous ligand 3-hydroxybutyrate and enhance its potency almost 10-fold. This suggests that the pyrazolopyrimidines may have therapeutic value when given alone.