137032-98-5

Upstream product

• 137051-59-3 3-Methoxy-2-methyl-3-phenyl-2-phenylselanyl-propionaldehyde 
• 15174-47-7 α-methyl-trans-cinnamaldehyde 
• 100-52-7 benzaldehyde 
• 189089-27-8 methyl 3-methoxy-3-phenyl-2-methylene-propanoate 
• 18020-59-2 methyl 3-hydroxy-2-methylidene-3-phenylpropionate 

Downstream Products

• 1353569-43-3 C₁₉H₁₈F₃NO₂ 
• 1353568-90-7 C₁₈H₁₉NO₂ 

Relevant academic research and scientific papers

Palladium-catalyzed oxidative aryltrifluoromethylation of activated alkenes at room temperature

A palladium-catalyzed intramolecular oxidative aryltrifluoromethylation reaction of activated alkenes has been explored. The reaction allows for an efficient synthesis of a variety of CF3-containing oxindoles. Preliminary mechanistic study indicated that the reaction involves a Csp 3-PdIV(CF3) intermediate, which undergoes reductive elimination to afford a Csp3-CF3 bond.

Facile Access to 2-Alkylidene 3-Oxy Propanals and Propionic Acids from Conjugated Enals

Conjugated enals or their methyl acetals react with benzeneselenyl chloride in the presence of oxygen nucleophile to give Michael-type adducts.The latter are oxidized into 2-alkylidene 3-oxy propanals and propionic acids.