13704-50-2Relevant academic research and scientific papers
Synthesis and antimicrobial activities of some polyphenol compounds by nano zno-tbab as a heterogeneous catalytic media
Ahmadinejad, Ali,Bargebid, Rahele,Khabnadideh, Soghra,Khalafi-Nezhad, Ali,Zamani, Leila,Zomorodian, Kamiar
, p. 203 - 211 (2021/03/19)
Introduction: Mannich reaction is a typical example of a three-component condensation reaction and the chemistry of Mannich bases has been the matter of search by researchers. Here, an efficient procedure for the synthesis of some new Mannich derivatives
Regioselective mannich reaction of phenols under high pressure using dichloromethane as C1 unit
Matsumoto, Kiyoshi,Joho, Kouta,Mimori, Seisuke,Iida, Hirokazu,Hamana, Hiroshi,Kakehi, Akikazu
scheme or table, p. 1061 - 1067 (2009/06/28)
Regioselectivity in Mannich reaction of 4-, 3-, and 2-substituted phenols with typical heterocyclic amines are investigated under reaction conditions developed by us. Phenol and 4-alkyl, and 4-chlorophenols in the title reaction predominantly gave the corresponding 2-(aminomethyl)phenols, while 4-methoxyphenol afforded, in addition to the mono(aminomethyl)phenols, a considerable amount of the bis adducts. Peculiarly enough, 3-methylphenol with amines afforded 3-methyl-4-(aminomethyl)phenols whereas 2-methylphenol produced 2-methyl-6-(aminomethyl)phenols.
2-(aminoalkoxy) phenylalkylamines with antiinflammatory activity
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, (2008/06/13)
Compounds of the formula I STR1 including pharmaceutically acceptable salts thereof are disclosed in which R1, R2, R3, and R4 independently represent hydrogen, hydroxy, halo, halogenated alkyl, halogenated alkox
