137044-53-2Relevant academic research and scientific papers
BETAINES FROM NEW HETEROCYCLIC PHENOLS: 9-OXIDO-PYRIDOPYRIMIDIN-5-IUM AND DERIVATIVES.
Dennin, F.,Blondeau, D.,Sliwa, H.
, p. 4307 - 4308 (1991)
9-Oxido-pyridopyrimidin-5-ium and its 2,4-dimethyl derivative were obtained from the corresponding hydroxy compounds by ion exchange on Amberlite IRA 401 S.
Studies toward the synthesis of cinachyramine. An efficient route to 1,5-diazabicyclo[4.4.0]dec-5-enes Dedicated to the memory of Professor Harry H. Wasserman
Barykina-Tassa, Olga V.,Snider, Barry B.
, p. 3151 - 3154 (2015)
Hydrogenation (3 atm) of readily available pyrido[1,2-a]pyrimidines 10, 14, and 17 over 5% Rh/Al2O3 forms 1,5-diazabicyclo[4.4.0]dec-5-enes 9, 15, and 18 in >95% yield, providing a general route to this little-studied class of compounds. All attempts to form the tetrahydro-1,2,4-triazine moiety of cinachyramine (1) by rearrangement of amidinium dimethylhydrazone 8 using the procedures developed by Kamatori to convert hydrazone 3a to tetrahydro-1,2,4-triazine 4a were unsuccessful.
SYNTHESIS, ELECTRONIC STRUCTURE, AND ABSORPTION SPECTRA OF 9-HYDROXYPYRIDOPYRIMIDINIUM DERIVATIVES
Palomino, M. I. Leon,Zaitsev, B. E.,Gashev, S. B.,Nikitin, S. V.,Smirnov, L. D.,Koval'chukova, O. V.
, p. 1110 - 1115 (2007/10/02)
Pyridopyrimidinium salt derivatives have been prepared by condensation of 2-aminopyridinium salts with β-dicarbonyl compounds.The acid-base equilibrium dissociation constants for 2,4-dimethyl-9-hydroxypyridopyrimidinium perchlorate have been measured, and the spectroscopic characteristics of its neutral, anionic, and cationic forms have been determined; the electronic absorption spectra of the neutral and anionic forms of 2,4-dimethyl-9-hydroxypyridopyrimidinium perchlorate have been interpreted based on this experimental and calculated data.
