1370446-52-8

Basic information

• Product Name: 2-[3-(3-fluorophenyl)-1-{4-[2-(morpholin-4-yl)ethyl]phenyl}-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]-N-(propan-2-yl)acetamide
• Synonyms: 2-[3-(3-fluorophenyl)-1-{4-[2-(morpholin-4-yl)ethyl]phenyl}-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]-N-(propan-2-yl)acetamide
• CAS NO: 1370446-52-8
• Molecular Weight: 467.543
• Mol File: 1370446-52-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[3-(3-fluorophenyl)-1-{4-[2-(morpholin-4-yl)ethyl]phenyl}-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]-N-(propan-2-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(3-fluorophenyl)-1-{4-[2-(morpholin-4-yl)ethyl]phenyl}-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]-N-(propan-2-yl)acetamide(1370446-52-8)
• EPA Substance Registry System: 2-[3-(3-fluorophenyl)-1-{4-[2-(morpholin-4-yl)ethyl]phenyl}-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]-N-(propan-2-yl)acetamide(1370446-52-8)

Safety Data

• Hazardous Substances Data: 1370446-52-8(Hazardous Substances Data)

Upstream product

• 75726-96-4 2-bromo-N-isopropylacetamide 
• 1370447-69-0 5-(3-fluorophenyl)-2-{4-[2-(morpholin-4-yl)ethyl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 100-27-6 2-(4-nitrophenyl)ethanol 
• 20020-28-4 <(p-Nitrophenyl)ethyl>-β-sulfonic ester 
• 210158-20-6 4-[2-(4-nitro-phenyl)-ethyl]-morpholine 
• 262368-47-8 4-[2-(4-morpholinyl)ethyl]aniline 
• 1370447-65-6 4-[2-(4-hydrazinylphenyl)ethyl]morpholine 
• 1370447-66-7 2-(3-fluorophenyl)(2-{4-[2-(morpholin-4-yl)ethyl]phenyl}hydrazinylidene)ethanoic acid 

Relevant articles and documents

1, 2, 4-TRIAZOLONE DERIVATIVE

The present invention provides a 1,2,4-triazolone derivative represented by Formula (1A) having an antagonistic activity on the arginine-vasopressin 1b receptor or a pharmaceutically acceptable salt thereof and provides a pharmaceutical composition comprising the compound or the salt as an active ingredient, in particular, a therapeutic or preventive agent exhibiting favorable pharmacokinetics in a disease such as mood disorder, anxiety disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal disease, drug addiction, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, head injury, inflammation, immune-related disease, or alopecia.