1370462-98-8

Basic information

• Product Name: 2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile
• Synonyms: 2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile
• CAS NO: 1370462-98-8
• Molecular Weight: 271.278
• Mol File: 1370462-98-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile(1370462-98-8)
• EPA Substance Registry System: 2-(2-oxo-1-phenylindolin-3-ylidene)malononitrile(1370462-98-8)

Safety Data

• Hazardous Substances Data: 1370462-98-8(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 91-56-5 indole-2,3-dione 
• 3335-98-6 1-phenyl-1,3-dihydro-indol-2-one 
• 109-77-3 malononitrile 
• 723-89-7 1-phenyl-indole-2,3-dione 

Downstream Products

• 1203488-25-8 2-amino-1',2',5,6,7,8-hexahydro-7,7-dimethyl-2',5-dioxo-1'-phenylspiro[4H-1-benzopyran-4,3'-[3H]indole]-3-carbonitrile 
• 1370462-64-8 (R)-methyl 2'-amino-3'-cyano-2-oxo-1-phenylspiro[indoline-3,4'-pyran]-6'-carboxylate 

Relevant articles and documents

A Simplistic Approach for Preparation of Alkylidenemalononitrile Derivatives: Characterization, In silico Studies, Quantum Chemical Evaluation, Molecular Docking, and In vitro Biological Activity Evaluation

A new and efficient green grinding-based catalyst free Knoevenagel condensation of aldehydes/ketones and malononitrile for the rapid preparation of twelve malononitrile derivatives (C1-C12) is proposed. Characterization of the derivatives was done by sup

Iron-catalyzed cross-dehydrogenative coupling of indolin-2-ones with active methylenes for direct carbon-carbon double bond formation

The iron-catalyzed cross-dehydrogenative coupling (CDC) of C(sp3)-H/C(sp3)-H bonds to afford olefins by 4H elimination is described. This method employs air (molecular oxygen) as an ideal oxidant, and is performed under mild, ligand-free and base-free conditions. H2O is the only byproduct. Good tolerance of functional groups and high yields have also been achieved. Preliminary mechanistic investigations suggest that the present transformation involves a radical process.

Ordered short channel mesoporous silica modified with 1,3,5-triazine-piperazine as a versatile recyclable basic catalyst for cross-aldol, Knoevenagel and conjugate addition reactions with isatins

A triazine-piperazine immobilized on ordered short channel mesoporous silica was synthesized, characterized and used as a heterogeneous basic catalyst in the synthesis of indole skeletal structures from isatin derivatives under ambient reaction conditions in good to excellent isolated yields. The catalyst showed no loss in its efficacy over 10 recycle experiments. This journal is