1370635-11-2

Upstream product

• 4703-95-1 3-(furan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one 
• 1314446-53-1 C₁₀H₆ClNO₂ 
• 617-89-0 furan-2-ylmethanamine 
• 17422-32-1 5-chloro-1H-indole 
• 883-55-6 2-(5-chloro-1H-indol-3-yl)-2-oxoacetyl chloride 

Relevant academic research and scientific papers

A facile synthesis of novel 3-(aryl/alkyl-2-ylmethyl)-2-thioxothiazolidin- 4-ones using microwave heating

(Z)-5-(2-(1H-Indol-3-yl)-2-oxoethylidene)-3-(aryl/alkyl-2-ylmethyl) -2-thioxothiazolidin-4-ones (7a-w) have been synthesized by the Knoevenagel condensation reaction of 3-(aryl/alkyl-2-ylmethyl)-2-thioxothiazolidin-4-ones (3a-d) with suitably substituted 2-(1H-indol-3-yl)2-oxoacetaldehydes (6a-g) under microwave conditions. The thioxothiazolidin-4-ones were prepared from the corresponding aryl/alkyl amines (1a-d) and di-(carboxymethyl)-trithiocarbonyl (2). The aldehydes (6a-g) were synthesized from the corresponding acid chlorides (5a-g) using HsnBu3.