13707-47-6

Basic information

• Product Name: Benzenesulfonamide, N-(2-furanylmethylene)-4-methyl-
• Synonyms: N-(furan-2-ylmethylene)-4-methylbenzenesulfonamide;2-furylCH=NTs;N-[(1E)-furan-2-ylmethylidene]-4-methylbenzene-1-sulfonamide;HMS2299D24
• CAS NO: 13707-47-6
• Molecular Formula: C12H11NO3S
• Molecular Weight: 249.29
• Mol File: 13707-47-6.mol
• Article Data: 39

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-(2-furanylmethylene)-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-(2-furanylmethylene)-4-methyl-(13707-47-6)
• EPA Substance Registry System: Benzenesulfonamide, N-(2-furanylmethylene)-4-methyl-(13707-47-6)

Safety Data

• Hazardous Substances Data: 13707-47-6(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 622-58-2 p-Tolylisocyanate 
• 70-55-3 toluene-4-sulfonamide 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 637019-57-9 (2R,5S,7S,1'R)-7-(N-tosylaminofuran-2-yl-methyl)-8-oxo-2-phenyl-2-methyl-1-aza-3-oxabicyclo[3.3.0]octane 
• 134340-63-9 (+/-)-4-methyl-N-(1-furan-2-ylpropyl)benzenesulfonamide 
• 825627-52-9 N-[(S)-3-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-diazo-1-furan-2-yl-3-oxo-propyl]-4-methyl-benzenesulfonamide 
• 595577-65-4 N-(1-furan-2-yl-2-methyl-propyl)-4-methyl-benzenesulfonamide 
• 134340-65-1 N-(1-(furan-2-yl)pentyl)-4-methylbenzenesulfonamide 
• 488720-06-5 N-(1,1-difuran-2-ylmethyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Desymmetrisation of meso difuryl alcohols, diols and their derivatives: Complementary directed and undirected asymmetric dihydroxylation reactions

Asymmetric reactions (for example, asymmetric epoxidation and asymmetric dihydroxylation) were examined for the desymmetrisation of the meso substrates 1,1-difuran-2-ylmethanol,N-(1,1-difuran-2-ylmethyl)-4- methylbenzenesulfonamide, (R,S)-1,4-difuran-2-yl

Chiral-Directing-Group-Assisted Rhodium(III)-Catalyzed Asymmetric Addition of Inert Arene C?H Bond to Aldimines with Subsequent Intramolecular Cyclization

By using a chiral directing group, an asymmetric rhodium(III)-catalyzed C?H bond addition to aldimines followed by intramolecular cyclization to form chiral isoindolinones has been achieved (up to 68 % yield, up to 93 % ee). A three-component variant that resembles Mannich reaction was also realized (41 % yield, 83 % ee). Product elaborations and preliminary mechanistic studies were described.

Divergent gold-catalysed reactions of cyclopropenylmethyl sulfonamides with tethered heteroaromatics

Cyclopropenylmethyl sulfonamides with tethered heteroaromatics have been demonstrated to undergo divergent gold-catalysed cyclisation reactions. A formal dearomative (4+3) cycloaddition takes place with furan-tethered substrates, yielding densely functionalised 5,7-fused heterocycles related to the bioactive curcusone natural products. Indole-tethered substrates display divergent reactivity giving biologically important tetrahydro-β-carbolines via a Friedel-Crafts mechanism.