13707-49-8

Upstream product

• 90-02-8 salicylaldehyde 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 1010721-86-4 C₁₈H₁₇NO₅S 
• 79807-50-4 N-(2-hydroxybenzyl)-4-methylbenzenesulfonamide 
• 1131440-08-8 N-[1-(2-hydroxyphenyl)propyl]-4-methylbenzene-sulfonamide 
• 1335012-63-9 methyl 2-methyl-4-(4-methylphenylsulfonamido)-4H-chromene-3-carboxylate 
• 1335012-50-4 ethyl 2-methyl-4-(4-methylphenylsulfonamido)-4H-chromene-3-carboxylate 
• 1335012-64-0 tert-butyl 2-methyl-4-(4-methylphenylsulfonamido)-4H-chromene-3-carboxylate 
• 1335012-65-1 isopropyl 2-methyl-4-((4-methylphenylsulfonamido))-4H-chromene-3-carboxylate 

Relevant academic research and scientific papers

Palladium-Catalyzed Direct Intramolecular C-N Bond Formation: Access to Multisubstituted Dihydropyrroles

A palladium-catalyzed intramolecular amination of alkenes with retention of olefin functionalization was achieved under mild reaction conditions. In the presence of palladium catalyst, the tosyl-protected amine can directly couple with a double bond to provide versatile dihydropyrrole derivatives in moderate to excellent yields.

Facile synthesis, antimicrobial and antiviral evaluation of novel substituted phenyl 1,3-thiazolidin-4-one sulfonyl derivatives

A series of novel substituted phenyl 1, 3-thiazolidin-4-one sulfonyl derivatives 5 (a-t) were synthesized and screened for their in-vitro anti-microbial and anti-viral activity. The result of the anti-microbial assay demonstrated compounds 5d, 5f, 5g, 5h,

A quick route for the synthesis of 3-Aryl-3,4-dihydro-2H-benz[e]-1,3- oxazin-2-ones

N-(2-Hydroxy)-benzyl-arylamines (1) gave substantially pure 3-aryl-3,4-dihydro-2H-benz[e]-1,3-oxazin-2-one 2 on cyclization with carbonyldiimidazole in DMSO in 20-30 min at 20-25 °C in excellent yields.

One step synthesis of benzoxazepine derivatives via a PPh3 catalyzed aza-MBH domino reaction between salicyl N-tosylimines and allenoates

PPh3-Catalyzed aza-MBH domino reaction of salicyl N-tosylimines with γ-CH3 substituted allenoates is reported. Readily available imines and allenoates are converted to benzoxazepine derivatives in one step. Wherein, functionalization

Synthesis of meso-tetraphenyl porphyrins via condensation of dipyrromethanes with N-tosyl imines

A new synthetic route for the synthesis of 5,10,15,20-tetraphenyl porphyrins has been developed based on the reaction of 5-substituted dipyrromethanes with N-tosyl imines in the presence of a metal triflate catalyst. meso-Substituted tetraphenyl porphyrins were synthesized in a two-step process. The first step of the method is the metal triflate-catalyzed condensation of 5-substituted dipyrromethanes with N-tosyl imines to form a porphyrinogen intermediate and the second step is the oxidation of the porphyrinogen to porphyrin. The method was applied to the synthesis of trans-A2B2-tetraarylporphyrins and the products were obtained with only a trace amount of one scrambling product. The synthesis of two important building blocks for porphyrin synthesis, mono and di-sulfonamide alkylated 5-substituted dipyrromethanes, was achieved by the addition of 5-substituted dipyrromethane to N-tosyl imine. The application of mono and di-sulfonamide alkylated 5-substituted dipyrromethanes in '2+2' porphyrin formation reactions is presented.