79807-50-4

Upstream product

• 79807-49-1 Acetic acid 2-{[(E)-toluene-4-sulfonylimino]-methyl}-phenyl ester 
• 75-30-9 2-iodo-propane 
• 13707-49-8 salicyl N-tosylimine 
• 932-30-9 2-Hydroxybenzylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 70-55-3 toluene-4-sulfonamide 
• 90-02-8 salicylaldehyde 
• 1576-37-0 N-benzyl-p-toluenesulfonamide 

Downstream Products

• 1096365-38-6 4-tosyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine 
• 1448061-75-3 3,4-dihydro-3-[(4-methylphenyl)sulfonyl]-2H-benz[e]-1,3-oxazin-2-one 

Relevant academic research and scientific papers

Amide Iridium Complexes As Catalysts for Transfer Hydrogenation Reduction of N-sulfonylimine

Sulfonamide moieties widely exist in natural products, biologically active substance, and pharmaceuticals. Here, an efficient water-soluble amide iridium complexes-catalyzed transfer hydrogenation reduction of N-sulfonylimine is developed, which can be carried out under environmentally friendly conditions, affording a series of sulfonamide compounds in excellent yields (96-98%). In comparison with organic solvents, water is shown to be critical for a high catalytic transfer hydrogenation reduction in which the catalyst loading can be as low as 0.001 mol %. These amide iridium complexes are easy to synthesize, one structure of which was determined by single-crystal X-ray diffraction. This protocol gives an operationally simple, practical, and environmentally friendly strategy for synthesis of sulfonamide compounds.

A quick route for the synthesis of 3-Aryl-3,4-dihydro-2H-benz[e]-1,3- oxazin-2-ones

N-(2-Hydroxy)-benzyl-arylamines (1) gave substantially pure 3-aryl-3,4-dihydro-2H-benz[e]-1,3-oxazin-2-one 2 on cyclization with carbonyldiimidazole in DMSO in 20-30 min at 20-25 °C in excellent yields.

Carbon radical addition to N-sulfonylimines mediated by triethylborane or zinc

The utility of N-sulfonylimines as radical acceptors was investigated under the different reaction conditions such as the stannyl radical-mediated addition reaction, the triethylborane-mediated tin-free radical reaction, and the zinc-mediated aqueous-medi

Bromoethylsulfonium salt-a more effective annulation agent for the synthesis of 6- and 7-membered 1,4-heterocyclic compounds

(Chemical Equation Presented) Reaction of bromoethylsulfonium salt with 1,2-/1,3-aminoalcohols gave six- and seven-membered rings in good-to-excellent yields. The reactions proceed through generation of a vinyl sulfonium salt followed by annulation to give 1,4-heterocyclic compounds such as morpholines and benzoxazepines in a simple procedure. The method accommodates a range of nitrogen substituents and the amino alcohol can be substituted by amino thiols and diamines to give thiomorpholines, piperazines and benzodiazepines.

Removal of Toluene-p-sulphonyl Groups from Sulphonamides. Part 5. Reactions of Phenylglyoxal Imines and some Tosylimines

Phenylglyoxal anil monomers have been shown to react with several nucleophilic reagents and the structures of the products have been elucidated.Various N-tosylarylimines also react with nucleophiles to give useful products.Phenacylimidates underwent cycloadditions with diphenylketen; such reactions gave complex results with phenacylimines, but the latter reacted with conjugated dienes in the presence of BF3 to give cycloaddition products in good yield.