1370731-52-4

Upstream product

• 1291780-42-1 N-(4-trifluoromethylbenzoyl)phenylalanine methyl ester 
• 753479-58-2 methyl 2-(4-(trifluoromethyl)phenyl)oxazole-4-carboxylate 
• 603-35-0 triphenylphosphine 
• 15816-25-8 4-(trifluoromethyl)benzenimidic acid ethyl ester hydrochloride 
• 66046-34-2 4-(trifluoromethyl)benzaldehyde oxime 
• 455-18-5 4-CF₃C₆H₄CN 
• 71-43-2 benzene 
• 1055051-35-8 methyl 2-[4-(trifluoromethyl)phenyl]-1,3-oxazoline-4-carboxylate 
• 455-19-6 4-Trifluoromethylbenzaldehyde 

Relevant academic research and scientific papers

Access to di- and trisubstituted oxazoles by NBS-mediated oxidative cyclisation of N-acyl amino acid derivatives

A remarkably simple method for the synthesis of di- and trisubstituted functionalised oxazoles under metal- and catalyst-free conditions is described. An iterative bromination and debromination of N-acylated amino acid derivatives with NBS as the sole rea

Aryl-aryl coupling via palladium-catalyzed C-P/C-H bond cleavage

The first example of aryl-aryl coupling through palladium-catalyzed C-P/C-H bond cleavage with good functional group tolerance is disclosed. This work demonstrates the phosphines could be used as coupling partners in palladium-catalyzed aryl-aryl coupling

Pd(ii)-catalyzed direct C5-arylation of azole-4-carboxylates through double C-H bond cleavage

The first palladium-catalyzed direct C5-arylation of azole-4-carboxylates with simple unactivated arenes through double C-H bond cleavage is realized. This protocol provided a straightforward access to diverse 5-arylsubstituted azole-4-carboxylic derivatives with good functional group tolerance. The Royal Society of Chemistry 2012.