137105-52-3

Basic information

• Product Name: 1-BROMO-2-(2,2-DIETHOXY-ETHYLSULFANYL)-BENZENE
• Synonyms: 1-BROMO-2-(2,2-DIETHOXY-ETHYLSULFANYL)-BENZENE;Benzene, 1-broMo-2-[(2,2-diethoxyethyl)thio]-;(2-broMophenyl)(2,2-diethoxyethyl)sulfane
• CAS NO: 137105-52-3
• Molecular Formula: C₁₂H₁₇BrO₂S
• Molecular Weight: 305.23
• Mol File: 137105-52-3.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-BROMO-2-(2,2-DIETHOXY-ETHYLSULFANYL)-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2-(2,2-DIETHOXY-ETHYLSULFANYL)-BENZENE(137105-52-3)
• EPA Substance Registry System: 1-BROMO-2-(2,2-DIETHOXY-ETHYLSULFANYL)-BENZENE(137105-52-3)

Safety Data

• Hazardous Substances Data: 137105-52-3(Hazardous Substances Data)

Usage

General Description

1-Bromo-2-(2,2-diethoxy-ethylsulfanyl)-benzene is a chemical compound with the molecular formula C12H17BrOS. It is a benzene derivative that contains a bromine atom and a diethoxy-ethylsulfanyl group attached to the benzene ring. 1-BROMO-2-(2,2-DIETHOXY-ETHYLSULFANYL)-BENZENE is commonly used in organic synthesis and medicinal chemistry as a building block for more complex molecules. It is known for its reactivity and ability to undergo various chemical reactions, making it a valuable tool for the synthesis of pharmaceuticals and other organic compounds. Additionally, the presence of the diethoxy-ethylsulfanyl group imparts unique chemical properties to the compound, making it useful in the development of new materials and technologies.

Upstream product

• 615-36-1 2-bromoaniline 
• 6320-02-1 o-bromothiophenol 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Downstream Products

• 59377-31-0 ((E)-2-Ethoxy-vinylsulfanyl)-benzene 
• 1423-61-6 7-bromobenzo(b)thiophene 

Relevant articles and documents

Intramolecular Formal anti-Carbopalladation/Heck Reaction: Facile Domino Access to Carbo- and Heterooligocyclic Dienes

An intramolecular domino process consisting of a formal anti-carbopalladation followed by Heck reaction is realized. Complex oligo(hetero)cyclic scaffolds are efficiently obtained in one synthetic step from easily obtainable enyne precursors. In contrast to common syn-carbopalladation reactions of alkyne units, the carbopalladation employed here is designed to afford an anti-arrangement of the two new substituents across the emerging double bond. A prerequisite is that the residues next to the alkyne should lack any β-hydrogen atoms. The method paves the way to tri- and tetrasubstituted double-bond systems that have not been accessible by conventional Pd catalysis.

INHIBITORS OF THE KYNURENINE PATHWAY

The present application provides novel inhibitors of indoleamine 2,3-dioxygenase-1 and/or indoleamine 2,3-dioxygenase-2 and/or tryptophan 2,3-dioxygenase, metabolites thereof, and phannaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. A therapeutically effective amount of one or more of the compounds of formula (I) is useful in treating diseases resulting from dysregulation of the kynurenine pathway. Compounds of formula (I) act by inhibiting the enzymatic activity or expression of indoleamine 2,3-dioxygenase-1 and/or indoleamine 2,3-dioxygenase-2 and/or tryptophan 2,3-dioxygenase.

Piperidine derivatives having effects on serotonin related systems

The present invention provides the compounds of the following formula: Wherein the variables are as defined in the specification and a method for inhibiting the reuptake of seretonin, antagonizing the 5-HT1Areceptor and antagonizing the 5-HT2Areceptor which comprises administering to a subject in need of such treatment an effective amount of the compound of above formula.