59377-31-0

Upstream product

• 137105-52-3 2-(2-bromophenylthio) acetaldehyde diethyl acetal 
• 6320-02-1 o-bromothiophenol 

Downstream Products

• 210416-90-3 (1Z,4Z)-1-Ethoxy-6,6-dimethyl-2,4-bis-phenylsulfanyl-hepta-1,4-dien-3-ol 
• 210416-92-5 (1Z,4Z,6Z)-1-Ethoxy-8,8-dimethyl-2,4,6-tris-phenylsulfanyl-nona-1,4,6-trien-3-ol 
• 210416-70-9 (Z)-1-Ethoxy-4,4-dimethyl-2-phenylsulfanyl-pent-1-en-3-ol 
• 59377-51-4 Cyclopentylidene-phenylsulfanyl-acetaldehyde 
• 37605-80-4 α-Phenylthio-cyclohexylidenacetaldehyd 
• 210416-82-3 (Z)-4,4-Dimethyl-2-phenylsulfanyl-pent-2-enal 
• 210416-93-6 (2E,4E,6E)-8,8-dimethyl-2,4,6-tris(phenylthio)nona-2,4,6-trienal 
• 210416-91-4 6,6-dimethyl-2,4-bis(phenylthio)hepta-2,4-dienal 

Relevant academic research and scientific papers

Rotenoid Synthesis by Wadsworth-Emmons Coupling and Mukaiyama Cyclisation: Application to 5-Thiorotenoids

A new synthesis of general applicability to rotenoid structures is described, through its specific objectives were 5-thiorotenoids.The synthons carrying the A/B- and the B/C-ring components are coupled by Wadsworth-Emmons synthesis and the ring B chromene is formed by Mukaiyama directed aldol cylisation: Michael addition completes the formation of the rotenoid at its correct oxidation state and in its stable cis-form.Examples with, and without 2,3-dimethoxylation in ring A are described.