137129-03-4

Basic information

• Product Name: Benzenemethanamine, N-(phenylmethyl)-N-(2,4,6-trimethylphenyl)-
• CAS NO: 137129-03-4
• Molecular Formula: C23H25N
• Molecular Weight: 315.458
• Mol File: 137129-03-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(phenylmethyl)-N-(2,4,6-trimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(phenylmethyl)-N-(2,4,6-trimethylphenyl)-(137129-03-4)
• EPA Substance Registry System: Benzenemethanamine, N-(phenylmethyl)-N-(2,4,6-trimethylphenyl)-(137129-03-4)

Safety Data

• Hazardous Substances Data: 137129-03-4(Hazardous Substances Data)

Upstream product

• 853955-69-8 [2-(hydroxymethyl)phenyl]dimethyl(phenyl)silane 
• 52742-32-2 N,N-dibenzyl-O-benzoylhydroxylamine 
• 75732-01-3 mesitylcopper(I) 
• 18982-54-2 o-bromobenzyl alcohol 
• 17100-66-2 2-(tetrahydropyranyloxy)methylbromobenzene 
• 853955-58-5 dimethyl(2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)phenyl)silane 
• 321903-29-1 1,1-dimethyl-1,3-dihydrobenzo[c][1,2]oxasilole 
• 100-39-0 benzyl bromide 
• 88-05-1 2,4,6-trimethylaniline 
• 5980-97-2 mesitylboronic acid 
• 214360-78-8 2,4,6-trimethylbenzeneboronic acid neopentyl glycol cyclic ester 
• 183677-71-6 2-(4-bromophenyl)-5,5-dimethyl-1,3,2-dioxaborinane 
• 576-83-0 2,4,6-trimethylphenyl bromide 

Downstream Products

• 88-05-1 2,4,6-trimethylaniline 

Relevant articles and documents

Catalytic Transfer Hydrodebenzylation with Low Palladium Loading

A highly-efficient catalytic system for hydrodebenzylation reaction is described. The cleavage of O-benzyl and N-benzyl protecting groups was performed using an uncommonly low palladium loading (0.02–0.3 mol%; TON up to 5000) in a relatively short reaction time. The approach was used for a variety of substrates including pharmaceutically important precursors, and gram-scale deprotection reaction was shown. Transfer conditions together with easy-to-make Pd/C catalyst are the key features of this debenzylation scheme. (Figure presented.).

Copper-catalyzed amination of arylboronates with N,N-dialkylhydroxylamines

A tolerant coupling: The title reaction has been developed to deliver arylamines (see scheme; Bz=benzoyl, dppbz=1,2-bis(diphenylphosphino)benzene). The catalysis is based on electrophilic, umpolung amination and enables the use of secondary acyclic amines. Various functional groups are tolerated, thus opening up a new substrate class for the Chan-Lam-type coupling.