137156-41-3 Usage
Uses
Used in Organic Synthesis:
Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate is used as a key intermediate in the synthesis of various organic compounds. Its triazole ring and carboxylic acid group provide a foundation for the creation of a wide range of molecules with diverse applications.
Used in Medicinal Chemistry:
EtOH-THC is employed as a building block in the development of new pharmaceuticals. Its unique structure allows for the design of molecules with potential therapeutic properties, making it a valuable asset in the field of medicinal chemistry.
Used in Anti-inflammatory Applications:
Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate has been studied for its potential anti-inflammatory properties. Its ability to modulate inflammatory pathways and reduce inflammation makes it a promising candidate for the development of new anti-inflammatory drugs.
Used in Anticancer Applications:
EtOH-THC and its derivatives have shown promising anticancer properties. They have the potential to target various cancer cells and inhibit their growth and proliferation, making them valuable in the development of novel cancer therapies.
Used in Drug Synthesis:
Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate is used as a starting material in the synthesis of various drugs. Its versatile structure allows for the creation of molecules with specific therapeutic effects, contributing to the advancement of pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 137156-41-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,1,5 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 137156-41:
(8*1)+(7*3)+(6*7)+(5*1)+(4*5)+(3*6)+(2*4)+(1*1)=123
123 % 10 = 3
So 137156-41-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3O3/c1-2-11-5(9)4-3-8(10)7-6-4/h3,10H,2H2,1H3
137156-41-3Relevant academic research and scientific papers
Synthesis and application of a novel coupling reagent, ethyl 1-hydroxy- 1H-1,2,3-triazole-4-carboxylate
Jiang, Lu,Davison, Amanda,Tennant, George,Ramage, Robert
, p. 14233 - 14254 (2007/10/03)
An optimal coupling reagent, ethyl 1-hydroxy-1H-1,2,3-triazole-4- carboxylate (HOCt), has been designed and synthesised for application to solid phase peptide synthesis using Fmoc chemistry. It is used in combination with carbodiimide reagents, has very high coupling efficiency, and does not absorb at 302nm, thus allowing real-time monitoring of each coupling cycle. Its applications in the synthesis of endothelin analogues and difficult sequences are also discussed.
40. Diazoaldehyde chemistry: Part 3. Synthesis of 4-acyl-1H-1,2,3-triazole derivatives
Sezer, Oezkan,Dabak, Kadir,Akar, Ahmet,Anac, Olcay
, p. 449 - 453 (2007/10/03)
Ten new α -diazo-β-oxoaldehydes were condensed with aniline, ammonia, hydroxylamine, and semicarbazide to yield new 4-acyl-(1-substituted)-1H-1,2,3-triazoles in moderate-to-good yields. The method is simple and regiospecific. The latter feature makes this method superior to the widely used acylacetylene + azide approach.
