1371569-77-5

Basic information

• Product Name: C₇H₁₁Cu
• Synonyms: C₇H₁₁Cu
• CAS NO: 1371569-77-5
• Molecular Weight: 158.71
• Mol File: 1371569-77-5.mol

Chemical Properties

• CAS DataBase Reference: C₇H₁₁Cu(CAS DataBase Reference)
• NIST Chemistry Reference: C₇H₁₁Cu(1371569-77-5)
• EPA Substance Registry System: C₇H₁₁Cu(1371569-77-5)

Safety Data

• Hazardous Substances Data: 1371569-77-5(Hazardous Substances Data)

Upstream product

• 7681-65-4 copper(l) iodide 
• 2203-80-7 5-methylhex-1-yne 

Downstream Products

• 1451264-99-5 dicyclohexyl(5-methylhex-1-yn-1-yl)phosphine-borane 
• 1350843-91-2 (5-methylhex-1-yn-1-yl)diphenylphosphine oxide 

Relevant articles and documents

Room-Temperature Alkynylation of Phosphine Oxides with Copper Acetylides: Practical Synthesis of Alkynylphosphine Oxides

An efficient procedure for the synthesis of alkynylphosphine oxides based on the oxidative alkynylation of secondary phosphine oxides with copper acetylides was developed. Activation with molecular oxygen in the presence of either a mixture of 1,2-dimethylimidazole and triethylamine or N-methylimidazole alone enabled the formal umpolung of the poorly nucleophilic copper acetylides, which were coupled with phosphine oxides under remarkably mild conditions. Notable features of this procedure are the availability of the starting materials, its user-friendliness, and its mild conditions, which allow the synthesis of complex alkynylphosphine oxides.

Unprecedented synthesis of alkynylphosphine-boranes through room-temperature oxidative alkynylation

An original and user-friendly synthesis of alkynylphosphine-boranes, useful building blocks in organic synthesis, based on an oxidative P-alkynylation reaction with readily available copper acetylides is reported. The ability of a secondary phosphine protected with a borane to undergo oxidative coupling without oxidation of the P-moiety is demonstrated for the first time. The reaction, which proceeds at room temperature, is applicable to the preparation of enantioenriched and structurally complex alkynylphosphine-boranes.