137157-22-3Relevant academic research and scientific papers
New Types of Spin-labelled Sugar and Nucleoside Analogs: Pyrrolidine, Morpholine and Piperidine N-Oxyls
Tronchet, Jean M. J.,Zosimo-Landolfo, Guido,Balkadjian, Mirna,Ricca, Alessandra,Zsely, Martina,et al.
, p. 4129 - 4132 (1991)
Analogs of blocked furanose (20) or pyranose sugars (i.e. 15) and of nucleosides (i.e. 23) in which the ring oxygen has been replaced with a -N(OH)- bridge have been prepared in generally good yields by a general reductive cyclization procedure preserving the configuration of the preexistant asymetric centers and proceeding stereoselectively (in more favorable cases stereospecifically) when creating a new asymetric center.The title compounds oxidised to nitroxide free radicals affording usable ESR spectra.Keywords: ESR; Nitroxides; Hydroxylamines; Reductive Cyclization; Nitrones
