
Tetrahedron Letters p. 4129 - 4132 (1991)
Update date:2022-08-04
Topics:
Tronchet, Jean M. J.
Zosimo-Landolfo, Guido
Balkadjian, Mirna
Ricca, Alessandra
Zsely, Martina
et al.
Analogs of blocked furanose (20) or pyranose sugars (i.e. 15) and of nucleosides (i.e. 23) in which the ring oxygen has been replaced with a -N(OH)- bridge have been prepared in generally good yields by a general reductive cyclization procedure preserving the configuration of the preexistant asymetric centers and proceeding stereoselectively (in more favorable cases stereospecifically) when creating a new asymetric center.The title compounds oxidised to nitroxide free radicals affording usable ESR spectra.Keywords: ESR; Nitroxides; Hydroxylamines; Reductive Cyclization; Nitrones
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