1371591-78-4

Basic information

• Product Name: tert-butyl 2-fluoro-4-{5-[(1S)-1-hydroxypropyl]-1,2,4-oxadiazol-3-yl}benzoate
• Synonyms: tert-butyl 2-fluoro-4-{5-[(1S)-1-hydroxypropyl]-1,2,4-oxadiazol-3-yl}benzoate
• CAS NO: 1371591-78-4
• Molecular Weight: 322.336
• Mol File: 1371591-78-4.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-fluoro-4-{5-[(1S)-1-hydroxypropyl]-1,2,4-oxadiazol-3-yl}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-fluoro-4-{5-[(1S)-1-hydroxypropyl]-1,2,4-oxadiazol-3-yl}benzoate(1371591-78-4)
• EPA Substance Registry System: tert-butyl 2-fluoro-4-{5-[(1S)-1-hydroxypropyl]-1,2,4-oxadiazol-3-yl}benzoate(1371591-78-4)

Safety Data

• Hazardous Substances Data: 1371591-78-4(Hazardous Substances Data)

Upstream product

• 872018-02-5 tert-butyl 4-cyano-2-fluorobenzoate 
• 164149-28-4 4-cyano-2-fluorobenzoic acid 
• 1371591-77-3 tert-butyl 4-{5-[(1S)-1-acetoxypropyl]-1,2,4-oxadiazol-3-yl}-2-fluorobenzoate 
• 1263483-74-4 tert-butyl 4-amino(hydroxyimino)methyl-2-fluorobenzoate 

Downstream Products

• 1371591-79-5 tert-butyl 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzoate 
• 1371591-49-9 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-N-[(2S)-2,3-dihydroxypropyl]-2-fluorobenzamide 
• 1371591-50-2 N-[(1S)-2-amino-1-(hydroxymethyl)-2-oxoethyl]-4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzamide 
• 1371591-51-3 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluoro-N-[(1R)-2-hydroxy-1-methylethyl]benzamide 
• 1371591-65-9 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluoro-N-[(1S)-3-hydroxy-1-(hydroxymethyl)propyl]benzamide 
• 1371591-67-1 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-N-[(1R,2R)-2,3-dihydroxy-1-methylpropyl]-2-fluorobenzamide 
• 1371591-80-8 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzoic acid 
• 1371591-87-5 tert-butyl 4-(5-{(1R)-1-[4-(2,2-dimethylpropanoyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzoate 
• 1371591-89-7 4-(5-{(1R)-1-[4-(2,2-dimethylpropanoyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzoic acid 
• 1371591-92-2 tert-butyl 4-(5-{(1R)-1-[4-(cyclobutylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzoate 
• 1371591-90-0 4-(5-{(1R)-1-[4-(cyclobutylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzoic acid 
• 1371591-97-7 tert-butyl 2-fluoro-4-{5-[(1R)-1-{4-[(1-fluorocyclopropyl)carbonyl]phenoxy}propyl]-1,2,4-oxadiazol-3-yl}benzoate 
• 1371591-99-9 2-fluoro-4-{5-[(1R)-1-{4-[(1-fluorocyclopropyl)carbonyl]phenoxy}propyl]-1,2,4-oxadiazol-3-yl}benzoic acid 
• 1371592-00-5 tert-butyl 2-fluoro-4-{5-[(1R)-1-(4-isobutyrylphenoxy)propyl]-1,2,4-oxadiazol-3-yl}benzoate 

Relevant articles and documents

N-HETERO-RING-SUBSTITUTED AMIDE DERIVATIVE

Compounds are provided having an excellent hypoglycemic effect and β cell- or pancreas-preserving effects or pharmaceutically acceptable salts thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause hyperglycemia due to abnormal glucose metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.

SUBSTITUTED PHENYLAZOLE DERIVATIVE

Compounds are provided having an excellent hypoglycemic effect and β cell- or pancreas-protecting effects, or pharmaceutically acceptable salts thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause hyperglycemia due to abnormal glucose metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.

ACYLBENZENE DERIVATIVE

Provided are compounds having an excellent hypoglycemic action and a β cell- or pancreas-protecting action or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.