164149-28-4

Basic information

• Product Name: 4-CYANO-2-FLUOROBENZOIC ACID
• Synonyms: 2-FLUORO-4-CYANOBENZOIC ACID;4-CYANO-2-FLUOROBENZOIC ACID;BENZOICACID,4-CYANO-2-FLUORO;4-Carboxy-3-fluorobenzonitrile;4-cyano-o-fluorobenzoic acid;o-fluoro-4-cyanobenzoic acid
• CAS NO: 164149-28-4
• Molecular Formula: C₈H₄FNO₂
• Molecular Weight: 165.12
• EINECS: -0
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;C8Nitrogen Compounds;C8 to C9Chemical Synthesis;Carbonyl Compounds;Carboxylic Acids;Cyanides/Nitriles;New Products for Chemical Synthesis;Organic Building Blocks
• Mol File: 164149-28-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 214-216°C
• Boiling Point: 326.3 °C at 760 mmHg
• Flash Point: 151.1 °C
• Appearance: White to pale brown/Powder or Crystalline Powder
• Density: 1.42 g/cm³
• Vapor Pressure: 0.00275mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.61±0.10(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 8051929
• CAS DataBase Reference: 4-CYANO-2-FLUOROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYANO-2-FLUOROBENZOIC ACID(164149-28-4)
• EPA Substance Registry System: 4-CYANO-2-FLUOROBENZOIC ACID(164149-28-4)

Safety Data

• Hazard Codes: Xi,T,Xn
• Statements: 22-36/37/38-41
• Safety Statements: 26-36/37/39-39
• RIDADR: 3439
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 164149-28-4(Hazardous Substances Data)

Usage

Chemical Properties

Off-white powder

Uses

4-Cyano-2-fluorobenzoic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

InChI:InChI=1/C9H9FO2/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-4H,5-6H2,(H,11,12)

Upstream product

• 170572-49-3 2-fluoro-4-cyanotoluene 
• 220389-15-1 4-cyano-2-fluoro-benzoic acid ethyl ester 

Downstream Products

• 937732-88-2 C₁₄H₁₆FN₃O 
• 604000-97-7 2-fluoro-4-formylbenzoic acid 
• 175596-01-7 methyl 4-cyano-2-fluorobenzoate 
• 1203952-62-8 4-cyano-2-fluoro-N-methylbenzamide 
• 335155-19-6 4-(((tert-butoxycarbonyl)amino)methyl)-2-fluorobenzoic acid 
• 1418293-46-5 2-fluoro-4-(N-hydroxycarbamimidoyl)-benzoic acid 
• 1418293-47-6 2-fluoro-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid 
• 1418292-71-3 (R)-N-(1-(dimethylamino)-3-methylbutan-2-yl)-2-fluoro-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 
• 1000512-15-1 (4-(aminomethyl)-2-fluorophenyl)methanol 
• 1436426-37-7 N-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenyl)-4-cyano-2-fluorobenzamide 
• 1436422-31-9 4-(aminomethyl)-N-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenyl)-2-fluorobenzamide 
• 872018-02-5 tert-butyl 4-cyano-2-fluorobenzoate 
• 1371592-02-7 N-cyclopenta-3-en-1-yl-4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]ethyl}-1,2,4-oxadiazol-3-yl)-2-fluorobenzamide 
• 1371591-49-9 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-N-[(2S)-2,3-dihydroxypropyl]-2-fluorobenzamide 

Relevant articles and documents

N-acylamino acid amide compounds and intermediates for preparation thereof

The present invention discloses the compound represented by the formula (I): wherein A represents the following formula (a-1) or the following formula (a-2): B represents the following formula (b): (wherein the symbols are each as defined in the specification) or a pharmaceutically acceptable salts thereof, and intermediates for the preparation thereof, which have excellent platelet aggregation inhibitory activity and other properties and useful as prophylactic or therapeutic agents for diseases associated with a fibrinogen receptor, thrombosis, infarction and the like.