137172-45-3

Upstream product

• 108-24-7 acetic anhydride 
• 51785-70-7 methyl 3,5-di-O-benzoyl-2-deoxy-L-erythro-pentofuranoside 
• 51885-64-4 1,2-O-isopropylidene-β-L-arabinofuranose 
• 164145-69-1 1(S)-[(2R)-1,4-dioxaspiro[4.5]decanyl]-3-buten-1-ol 
• 103763-14-0 (3aR,5S,6S,6aR)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-ol 
• 103763-12-8 5-O-tert-butyldiphenylsilyl-α,β-L-arabinofuranose 
• 98-88-4 benzoyl chloride 
• 77772-43-1 5-O-benzoyl-L-arabinose diethyl dithioacetal 
• 43179-48-2 L-arabinose di(ethylthio)acetal 
• 5328-37-0 L-arabinose 
• 6893-72-7 5-O-benzoyl-1,2-O-isopropylidene-β-L-arabinofuranose 
• 3080-31-7 3,5-di-O-benzoyl-1,2-O-isopropylidene-β-L-arabinofuranose 
• 30591-84-5 methyl 3,5-di-O-benzoyl-L-arabinofuranoside 

Downstream Products

• 10356-76-0 5-fluoro-2'-deoxycytidine 

Relevant academic research and scientific papers

A chiral template-driven synthesis of a 3′-deoxy-3′-18F-fluorothymidine precursor

An asymmetric synthesis of a 3′-deoxy-3′-18F-fluorothymidine (18F-FLT) precursor has been developed wherein the deoxysugar moiety was synthesized using a novel Ga-mediated allylation of (R)-2,3-cyclohexylideneglyceraldehyde as the key step. The synthesis deviates significantly from the previous syntheses of the 18F-FLT precursors wherein the expensive starting material, thymidine was used.

Preparation of new acylated derivatives of L-arabinofuranose and 2-deoxy-L-erythro-pentofuranose as precursors for the synthesis of L-pentofuranosyl nucleosides

1,2-Di-O-acetyl-3,5-di-O-benzoyl-L-rabinofuranose and 1-O-acetyl-3,5-di-O-benzoyl-2-deoxy-L-erythro-pentofuranose have been synthesised from L-rabinose for use in the preparation of L-pentofuranosyl nucleosides. 1,2-Di-O-acetyl-3,5-di-O-benzoyl-L-arabinof