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137196-67-9

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137196-67-9 Usage

Uses

SDZ 205-557 is a SR-3 and SR-4 antagonist. It is a salt free analogue of SDZ 205-557 Hydrochloride (S211000).

Biological Activity

5-HT 3 /5-HT 4 receptor antagonist.

Check Digit Verification of cas no

The CAS Registry Mumber 137196-67-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,1,9 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 137196-67:
(8*1)+(7*3)+(6*7)+(5*1)+(4*9)+(3*6)+(2*6)+(1*7)=149
149 % 10 = 9
So 137196-67-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H21ClN2O3.ClH/c1-4-17(5-2)6-7-20-14(18)10-8-11(15)12(16)9-13(10)19-3;/h8-9H,4-7,16H2,1-3H3;1H

137196-67-9 Well-known Company Product Price

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  • Sigma

  • (S174)  SDZ-205,557 hydrochloride  solid

  • 137196-67-9

  • S174-5MG

  • 2,309.58CNY

  • Detail
  • Sigma

  • (S174)  SDZ-205,557 hydrochloride  solid

  • 137196-67-9

  • S174-25MG

  • 8,067.15CNY

  • Detail

137196-67-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name SDZ-205,557 hydrochloride

1.2 Other means of identification

Product number -
Other names 4-Amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:137196-67-9 SDS

137196-67-9Downstream Products

137196-67-9Relevant articles and documents

Drug evolution concept in drug design: 1. Hybridization method

Lazar, Carmen,Kluczyk, Alicja,Kiyota, Taira,Konishi, Yasuo

, p. 6973 - 6982 (2007/10/03)

A novel concept, "drug evolution", is proposed to develop chemical libraries that have a high probability of finding drugs or drug candidates. It converts biological evolution into chemical evolution. In this paper, we present "hybridization" drug evolution, which is the equivalent of sexual recombination of parental genomes in biological evolution. The hybridization essentially shuffles the building blocks of the parent drugs and ought to drug(s); no drug evolution can otherwise occur. We hybridized two drugs, benzocaine and metoclopramide and generated 16 molecules that include the parent drugs, four known drugs, and two molecules whose therapeutic activities are reported. The unusually high number of drugs and drug candidates in the library encourages high expectations of finding new drug(s) or drug candidate(s) within the remaining eight compounds. Interestingly, the therapeutic applications of the eight drugs or drug candidates in the library are fairly diverse as 38 therapeutic applications and 25 molecular targets are counted. Therefore, the library fits as a general chemical library for unspecified therapeutic activities. The hybridization of other two drugs, aspirin and cresotamide, is also described to demonstrate the generality of the method.

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