1372129-84-4

Upstream product

• 50-84-0 2,4 dichlorobenzoic acid 
• 101495-62-9 methyl 2,4-dichloro-5-nitrobenzoate 
• 873-74-5 4-Aminobenzonitrile 
• 19861-62-2 2,4-dichloro-5-nitrobenzoic acid 

Downstream Products

• 1372129-85-5 N₁-(4'-cyanophenyl)-5-(2'',6''-dimethyl-4''-formylphenoxy)-4-methoxycarbonyl-2-nitroaniline 
• 1622438-23-6 C₂₄H₁₈N₄O₅ 
• 1622438-26-9 C₂₄H₂₀N₄O₄ 
• 1538625-04-5 C₂₅H₂₀N₄O₅ 
• 1538624-97-3 C₂₃H₂₀N₄O₂ 
• 1538625-01-2 C₂₄H₂₃N₅O 
• 1538625-03-4 C₂₆H₂₅N₅O 
• 1538625-07-8 C₂₆H₂₇N₅O₂ 
• 1538625-09-0 C₂₈H₃₀N₆O 
• 1538625-15-8 C₂₆H₂₆N₄O₂ 
• 1538625-14-7 C₂₄H₂₂N₄O₂ 
• 1538625-05-6 C₂₅H₂₂N₄O₃ 
• 1538624-96-2 N-(4'-cyanophenyl)-5-(4-cyano-2,6-dimethylphenoxy)-4-hydroxymethyl-2-nitroaniline 
• 1538625-00-1 C₂₄H₂₁N₅O₃ 

Relevant academic research and scientific papers

Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors

The current optimization of 2,4-diarylaniline analogs (DAANs) on the central phenyl ring provided a series of new active DAAN derivatives 9a-9e, indicating an accessible modification approach that could improve anti-HIV potency against wild-type and resis

META-DIARYLANILINE OR META-DIARYLPYRIDINAMINE COMPOUND, PREPARATION METHOD AND MEDICAL USES THEREOF

Meta-diarylaniline or meta-diarylpyridinamine compounds, methods for preparing the same and uses thereof in manufacture of a medicament. The compounds according to the present application have strong inhibitory activity (at nM level) against wild-type and various drug-resistant HIV viral strains, exhibit good druggability, and can be easily synthesized.

Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates

Twenty-one new 4-substituted diarylaniline compounds (DAANs) (series 13, 14, and 15) were designed, synthesized, and evaluated against wildtype and drug resistant HIV-1 viral strains. As a result, approximately a dozen new DAANs showed high potency with l