137214-29-0Relevant academic research and scientific papers
Syntheses of 13C- and 14C-labelled trans-2-amino-2-methyl-N-(4-nitroxycyclohexyl)-propionamide (BM 12.1179)
Neidlein,Strein,Pressmar,Kramer,Michel
, p. 727 - 732 (2007/10/02)
The 13C- and 14C-labelled derivatives of the vasodilating nitric acid ester trans-2-amino-2-methyl-N-(4-nitroxycyclohexyl)-propionamide (BM 12.1179) (1) have been synthesized starting from the sterically hindered α-amino-isobutyric acid (2) via the oxazolone (synthesis of 13C-BM 12.1179) and the acid chloride (synthesis of 14C-BM 12.1179). Various amine-protecting groups and methods for activating the carboxy-function are compared.
