1372155-72-0Relevant academic research and scientific papers
The regioselective switch for amino-NHC mediated C-H activation of benzimidazole via Ni-Al synergistic catalysis
Shih, Wei-Chun,Chen, Wen-Ching,Lai, Ying-Chieh,Yu, Ming-Shiuan,Ho, Jhao-Jhe,Yap, Glenn P. A.,Ong, Tiow-Gan
supporting information; experimental part, p. 2046 - 2049 (2012/06/18)
We have disclosed a new mode of a chemically regioselective switch for C-H bond functionalization of benzimidazole derivatives via a cooperative effect invoked by Ni-Al bimetallic catalysis to create a steric requirement for obtaining the linear product of styrene insertion. Yet, excluding the AlMe 3 cocatalyst switches the reaction toward branch selectivity.
