1372173-48-2Relevant academic research and scientific papers
A single step approach to piperidines via ni-catalyzed β-carbon elimination
Kumar, Puneet,Louie, Janis
, p. 2026 - 2029 (2012)
An easy and expeditious route to substituted piperidines is described. A Ni-phosphine complex was used as catalyst for [4 + 2] cycloaddition of 3-azetidinone and alkynes. The reaction has broad substrate scope and affords piperidines in excellent yields a
Synthesis of enantiopure dehydropiperidinones from α-amino acids and alkynes via azetidin-3-ones
Ishida, Naoki,Yuhki, Tatsuya,Murakami, Masahiro
supporting information; experimental part, p. 3898 - 3901 (2012/09/22)
Chiral dehydropiperidinones were synthesized in enantiopure form from α-amino acids and alkynes via azetidin-3-ones.
Regioselective cycloaddition of 3-azetidinones and 3-oxetanones with alkynes through nickel-catalysed carbon-carbon bond activation
Ho, Kelvin Y. T.,Aissa, Christophe
supporting information; experimental part, p. 3486 - 3489 (2012/05/19)
Get in the ring! The first examples of transition-metal-catalysed C-C bond activation of 3-azetidinones and 3-oxetanones are reported. In the presence of a nickel catalyst and alkynes, a regioselective and high-yielding [4+2] cycloaddition occurs, leading to the formation of pyridinones, pyranones and eventually 4,5-disubstituted 3-hydroxypyridines (see scheme). Copyright
