Trimethylsilyl-N-phenyl-N'-<3-methyl-phenyl>-harnstoff, also known as N-(3-methylphenyl)-N'-phenyl-N''-trimethylsilyl-urea, is an organic compound with the molecular formula C17H22N2OSi. It is a derivative of urea, featuring a trimethylsilyl group (SiMe3) attached to the nitrogen atom, and two aryl groups (phenyl and 3-methylphenyl) connected to the other nitrogen atom. Trimethylsilyl-N-phenyl-N'-<3-methyl-phenyl>-harnstoff is primarily used as a protecting group in organic synthesis, particularly in the protection of amines and amides, due to its stability and ease of removal under mild conditions. The trimethylsilyl group can be selectively removed using fluoride ions, such as tetra-n-butylammonium fluoride (TBAF), to regenerate the free amine or amide.
13722-23-1
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Basic information
- Product Name: Trimethylsilyl-N-phenyl-N'-<3-methyl-phenyl>-harnstoff
- Synonyms:
- CAS NO:13722-23-1
- Molecular Formula:
- Molecular Weight: 298.46
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Trimethylsilyl-N-phenyl-N'-<3-methyl-phenyl>-harnstoff(CAS DataBase Reference)
- NIST Chemistry Reference: Trimethylsilyl-N-phenyl-N'-<3-methyl-phenyl>-harnstoff(13722-23-1)
- EPA Substance Registry System: Trimethylsilyl-N-phenyl-N'-<3-methyl-phenyl>-harnstoff(13722-23-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 13722-23-1(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 13722-23-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,2 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.Calculate Digit Verification of CAS Registry Number 13722-23:
(7*1)+(6*3)+(5*7)+(4*2)+(3*2)+(2*2)+(1*3)=81
81 % 10 = 1
So 13722-23-1 is a valid CAS Registry Number.
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Trimethylsilyl-N-phenyl-N'-<3-methyl-phenyl>-harnstoff
