13722-95-7

Basic information

• Product Name: 4-hydroxy-5-nitrosalicylate
• Synonyms: 4-hydroxy-5-nitrosalicylate
• CAS NO: 13722-95-7
• Molecular Weight: 227.174
• Mol File: 13722-95-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-5-nitrosalicylate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-5-nitrosalicylate(13722-95-7)
• EPA Substance Registry System: 4-hydroxy-5-nitrosalicylate(13722-95-7)

Safety Data

• Hazardous Substances Data: 13722-95-7(Hazardous Substances Data)

Downstream Products

• 13722-96-8 2,4-dihydroxy-5-nitrobenzoic acid 
• 3163-07-3 4-nitroresorcinol 

Relevant articles and documents

PYRIMIDINES-19. RING TRANSFORMATION OF 5-NITROURACIL INTO NITRORESORCINOLS

The first intermolecular ring transformation of a uracil derivative into benzene system is reported.Treatment of 1,3-dimethyl-5-nitrouracil (1) with acetone in NaOMe/MeOH afforded 6-acetonyl-5,6-dihydro-1,3-dimethyl-5-nitrouracil (6) wich was converted into 4-nitroresorcinol (5) upon treatment with NaOEt/EtOH at reflux.Reaction of 1 with butanone gave two major products, 3-(5,6-dihydro-1,3-dimethyl-5-nitrouracil-6-yl)-butanone (7) and 1-(uracil-6-yl)butanone isomer (8).Prolonged treatment of 7 with NaOEt/EtOH afforded 4-methyl-6-nitro-resorcinol (9) whereas 8 was converted into 2-methyl-4-nitro-resorcinol (10).Treatment of 1 with diethyl acetonedicarboxylate in NaOEt/EtOH afforded diethyl-2-(5,6-dihydro-1,3-dimethyl-5-nitrouracil-6-yl)-acetonedicarboxylate (2).Prolonged treatment of 2 with NaOEt/EtOH at reflux afforded (5,6-dihydro-1,3-dimethyl-6-nitrouracil-6-yl)acetic acid (3).Apparently, 2 underwent a retroClaisen reaction to give 3.Reaction of 1 with ethyl acetoacetate in NaOEt/EtOH gave adduct isomers 4 which underwent transformation reaction to give eventually 6-nitroresorcinol (5).