13722-96-8

Usage

Uses

Used in Organic Synthesis:
2,4-dihydroxy-5-nitrobenzoic acid is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, contributing to the formation of a wide range of organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4-dihydroxy-5-nitrobenzoic acid is used as a precursor for the development of new drugs, leveraging its chemical properties to create medicinal compounds with potential therapeutic applications.
Used in Agricultural Industry:
2,4-dihydroxy-5-nitrobenzoic acid is utilized in the agricultural sector for its antibacterial and antifungal properties, serving as a component in the production of agrochemicals to protect crops from diseases.
Used in Pigment and Dye Synthesis:
2,4-dihydroxy-5-nitrobenzoic acid is a key intermediate in the synthesis of pigments and dyes, where its chemical structure is essential for creating a variety of colorants used in different industries.
Used as a pH Indicator:
In chemical laboratory experiments, 2,4-dihydroxy-5-nitrobenzoic acid is employed as a pH indicator, helping to measure and monitor the acidity or alkalinity of solutions.

Upstream product

• 89-86-1 4-hydroxysalicylic acid 
• 13722-95-7 4-hydroxy-5-nitrosalicylate 
• 7697-37-2 nitric acid 
• 271261-71-3 2,4-dihydroxy-5-nitro-benzoic acid methyl ester 
• 108-46-3 recorcinol 

Downstream Products

• 81574-75-6 2,4-dimethoxy-5-nitro-benzoic acid methyl ester 
• 59036-73-6 2,4-diethoxy-5-nitro-benzoic acid ethyl ester 
• 271261-71-3 2,4-dihydroxy-5-nitro-benzoic acid methyl ester 
• 3163-07-3 4-nitroresorcinol 
• 69938-56-3 5-amino-2,4-dihydroxybenzoic acid 
• 855875-92-2 3-chloro-2,4-dihydroxy-5-nitro-benzoic acid 
• 22604-84-8 2,4-dihydroxy-3,5-dinitro-benzoic acid 
• 720672-26-4 3-bromo-2,4-dihydroxy-5-nitro-benzoic acid 
• 15719-64-9 methylammonium carbonate 
• 874210-23-8 2,4-bis[3-(ethoxycarbonyl)propoxy]-5-nitrobenzoic acid 
• 271261-72-4 5-nitro-2,4-bis(octyloxy)benzoic acid methyl ester 
• 874210-16-9 2,4-bis[3-(tert-butoxycarbonyl)propoxy]-5-nitrobenzoic acid methyl ester 
• 874210-15-8 2,4-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-5-nitrobenzoic acid methyl ester 
• 874210-20-5 2,4-bis[3-(tert-butoxycarbonyl)propoxy]-5-nitrobenzoic acid 

Relevant academic research and scientific papers

Multiturn Hollow Helices: Synthesis and Folding of Long Aromatic Oligoamides

Aromatic oligoamides adopting helical conformations are synthesized by coupling carboxyl-terminated basic units having two, four, and eight residues to amine-terminated oligomer precursors. Coupling yields show no noticeable reduction with the size of the

Preparation method for 5-amino-2,4-dihydroxybenzoic acid

The invention provides a preparation method for 5-amino-2,4-dihydroxybenzoic acid. The method comprises the steps that the raw material 2,4-dihydroxybenzoic acid is provided; the 2,4-dihydroxybenzoicacid is subjected to a nitration reaction to generate 5-

Synthesis method of 5-amino-2, 4-dihydroxybenzoic acid

The invention relates to a synthetic method of 5-amino-2, 4-dihydroxybenzoic acid, which comprises the following steps: with resorcinol as a raw material, carrying out Koble-Schmitt reaction to obtain2,4-dihydroxybenzoic acid; performing nitration reaction on 2,4-dihydroxybenzoic acid to obtain 5-nitro-2,4-dihydroxybenzoic acid; and carrying out reduction reaction on 5-nitro-2,4-dihydroxybenzoicacid to obtain a product 5-amino-2,4-dihydroxybenzoic acid. The method has the advantages of easy control of reaction process parameters, easily available raw materials, short reaction time, simple post-treatment, high atom utilization rate, high purity and high industrial feasibility.

CAVITY-CONTAINING OLIGOMERS AND POLYMERS EFFECTIVE IN CRYOPRESERVATION

The present invention provides compositions and methods for cryopreservation utilizing aromatic cavity-containing oligomers and polymers that contain structural motifs capable of shape-inducing intramolecular bonding to form cavities. The cavity-containin

Diversity-oriented synthesis for novel, selective and drug-like inhibitors for a phosphatase from Mycobacterium tuberculosis

Mycobacterium protein tyrosine phosphatase B (mPTPB) is a potential drug target of tuberculosis (TB). Using small molecule inhibitors of mPTPB could be a treatment to overcome emerging TB drug resistance. Using a Diversity-Oriented Synthesis (DOS) strateg

Nitration of some aromatic compounds by sodium nitrate in the presence of benzyltriphenylphosphonium peroxodisulfate

A simple, mild, and regioselective method for the nitration of some aromatic compounds using sodium nitrate in the presence of benzyltriphenylphosphonium peroxodisulfate in acetonitrile as solvent is reported. Mild reaction conditions and good to excellent yields of the products are the noteworthy advantages of the method. Copyright Taylor & Francis Group, LLC.

ORGANIC COMPOUNDS

Compounds of the formula are inhibitors of protein tyrosine phosphatases (PTPases) and, thus, may be employed for the treatment of conditions mediated by PTPase activity. The compounds of the present invention may also be employed as inhibitors of other enzymes characterized with a phosphotyrosine binding region such as the SH2 domain. Accordingly, the compounds of formula (I) may be employed for prevention and/or treatment of insulin resistance associated with obesity, glucose intolerance, diabetes mellitus, hypertension and ischemic diseases of the large and small blood vessels, conditions that accompany type-2 diabetes, including hyperlipidemia, hypertriglyceridemia, atherosclerosis, vascular restenosis, irritable bowel syndrome, pancreatitis, adipose cell tumors and carcinomas such as liposarcoma, dyslipidemia, and other disorders where insulin resistance is indicated. In addition, the compounds of the present invention may be employed to treat and/or prevent cancer (such as prostate or breast cancer), osteoporosis, neurodegenerative and infectious diseases, and diseases involving inflammation and the immune system.

Synthesis of crescent aromatic oligoamides

This article describes the synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in recent years in our laboratory. The large-scale preparation of a variety of monomers derived from various tetrasubstituted benzenes is presented. Three different strategies for constructing various oligomers consisting of meta- and meta/para-linked benzene residues are discussed. Factors affecting coupling efficiency and yields are analyzed. The developed synthetic methods have provided the basis for the preparation of longer oligomers and for the development of solid-phase synthesis.

Decarboxylative Nitration of Some Simple Hydroxybenzoic Acids Using Cerium(IV) Ammonium Nitrate

The mechanistic pathways proposed earlier in the Ce(IV) induced decarboxylation of aromatic acids have been examined in the light of new observations made.A simple, non-explosive, easy to control substitute to Bechman and Biermann's decarboxylative nitration is described and a plausible mechanism suggested.