1372420-85-3Relevant academic research and scientific papers
Asymmetric Mannich reaction between (S)-N-(tert-butanesulfinyl)-3,3,3- trifluoroacetaldimine and malonic acid derivatives. Stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids
Shibata, Norio,Nishimine, Takayuki,Shibata, Naoyuki,Tokunaga, Etsuko,Kawada, Kosuke,Kagawa, Takumi,Acena, Jose Luis,Sorochinsky, Alexander E.,Soloshonok, Vadim A.
, p. 1454 - 1462 (2014)
Inorganic as well as organic base catalysis was found to be effective for diastereoselective Mannich additions of malonic acid derivatives to (S S)-N-(tert-butanesulfinyl)-3,3,3-trifluoroacetaldimine. In the presence of catalytic amounts of ino
Organic base-catalyzed stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids
Shibata, Norio,Nishimine, Takayuki,Shibata, Naoyuki,Tokunaga, Etsuko,Kawada, Kosuke,Kagawa, Takumi,Sorochinsky, Alexander E.,Soloshonok, Vadim A.
supporting information; experimental part, p. 4124 - 4126 (2012/06/18)
Organic base-catalyzed reaction of (S)-N-tert-butanesulfinyl (3,3,3)-trifluoroacetaldimine with dialkyl malonates was found to be effective for synthesis of both (S,SS) and (R,SS) β-aminomalonates in high yield with good to excellent
