137247-85-9Relevant academic research and scientific papers
Evaluation of xanthine oxidase inhibitor properties on isoindoline-1,3-dion derivatives and calculation of interaction mechanism
Gundu?du, ?zlem,Noma, Samir Abbas Ali,Taskin-Tok, Tugba,Ate?, Burhan,Kishali, Nurhan
, (2020)
The aim of the present study was to synthesis of isoindole-1,3(2H)-dione (Phthalimides) derivatives and to investigation the inhibition of xanthine oxidase (XO). In study, xanthine oxidase inhibitory activities of complexes were observed in the range from
Investigation of the inhibitory effects of isoindoline-1,3-dion derivatives on hCA-I and hCA-II enzyme activities
Nadaroglu, Hayrunnisa,Gungor, Azize Alayl?,Gundogdu, ?zlem,Kishali, Nurhan Horasan,Sever, Belgin,Altintop, Mehlika Dilek
, p. 386 - 392 (2019/07/31)
Inhibition of carbonic anhydrase (CA) has emerged as a promising approach for the treatment of a variety of diseases such as glaucoma, epilepsy, obesity and cancer. As a result, the design of CA inhibitors (CAIs) is an outstanding field of medicinal chemi
