1372527-75-7Relevant academic research and scientific papers
Novel compounds containing multiple guanide groups that bind the HIV coreceptor CXCR4
Wilkinson, Royce A.,Pincus, Seth H.,Shepard, Joyce B.,Walton, Sarah K.,Bergin, Edward P.,Labib, Mohamed,Teintze, Martin
, p. 255 - 263 (2011/12/15)
The G-protein-coupled receptor CXCR4 acts as a coreceptor for human immunodeficiency virus type 1 (HIV-1) infection, as well as being involved in signaling cell migration and proliferation. Compounds that block CXCR4 interactions have potential uses as HI
