1372610-96-2Relevant academic research and scientific papers
Synthesis of Structurally Diversified Benzo[c]chromene Derivatives under (An)aerobic Conditions Catalyzed by CuI
Dong, Fang,Liu, Jian-Quan,Wang, Xiang-Shan
, p. 2822 - 2830 (2019)
2-Bromobenzoic acids underwent an α-arylation with cyclohexane-1,3-diones to give 1H-benzo[c]chromene-1,6(2H)-diones under Ar atmosphere catalyzed by CuI/l-proline in the presence of Cs2CO3. The subsequent regioselective oxidation took place under O2 balloon automatically based on the substituents for the construction of structurally diversified benzo[c]coumarin derivatives.
Tandem reactions leading to benzo[c]chromen-6-ones and 3-substituted isocoumarins
Fan, Xuesen,He, Yan,Cui, Liangyan,Guo, Shenghai,Wang, Jianji,Zhang, Xinying
, p. 673 - 677 (2012/03/10)
A simple and convenient protocol for the synthesis of benzo[c]chromen-6- ones and 3-substituted isocoumarins through a CuI-catalyzed tandem reaction of 2-bromobenzoates withcyclohexane-1,3-diones or acyclic 1,3-diones is developed. This strategy can also be extended to the one-pot synthesis of isoquinolin-1(2H)-one and 3,4-dihydrophenanthridine-1,6(2H,5H)-dione. A simple and convenient protocol for the synthesis of benzo[c]chromen-6-ones and 3-substituted isocoumarins through a CuI-catalyzed tandem reaction of 2-bromobenzoates with cyclohexane-1,3-dione or acyclic 1,3-dione has been developed. This strategy can also be extended to the one-pot synthesis of isoquionlin-1(2H)-one and 3,4-dihydrophenanthridine-1,6-(2H,5H)-dione. Copyright
