1372687-98-3Relevant academic research and scientific papers
Syntheses and reactivity of alkyl 1-[ N-(2-chloro-5-nitro-phenyl)- benzimidoyl] thioureas
Fathalla, Walid,Ali, Ibrahim. A.I.,Marek, Jaromir,Pazdera, Pavel
experimental part, p. 49 - 63 (2012/06/30)
A series of new alkyl 1-[N-(2-chloro-5-nitro-phenyl)-benzimidoyl] thioureas 3a-h were prepared from benzamides 1a-c. Benzimidoyl thioureas 3a-e afforded 5-nitro-2-phenyl-benzothiazole 5a-c under basic conditions via thiourea-isothiourea rearrangement and SNAr. A mechanistic rationalization supported by the direct formation of benzothioamide 8 and bis-benzimidoyl sulfide 9 derivatives from the reaction of imidoyl isothiocyanate 2 with bulky amines was supported.
