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Upstream product

• 7686-29-5 2-amino-4-nitrobenzenethiol 
• 4433-52-7 2,3-dihydro-benzothiazole 
• 33802-08-3 4-methyl-N-(3-nitro-phenyl)-benzamide 
• 874-60-2 4-methyl-benzoyl chloride 
• 99-09-2 3-nitro-aniline 
• 1372687-98-3 3-phenyl-1-[N-(2-chloro-5-nitro-phenyl)-4-methylbenzimidoyl]thiourea 
• 347909-69-7 C₁₄H₁₁ClN₂O₃ 

Relevant academic research and scientific papers

SnCl2 catalyzed direct synthesis of pyrroles under aqueous conditions

Synthetic substituted pyrroles are related with interesting biological activities, yet they remain inadequately explored within drug discovery. Late years have seen a growing interest in synthetic approaches that can provide access to structurally novel pyrroles so that the biological usefulness of this compound class can be more fully investigated. Herein, an efficient and versatile practical protocol for the pyrroles using stannous(II) chloride dihydrate as catalyst is described under aqueous conditions at 55 oC in high yields. Also, this method is applicable for the preparation of diversity and oriented pyrrole derivatives.

Syntheses and reactivity of alkyl 1-[ N-(2-chloro-5-nitro-phenyl)- benzimidoyl] thioureas

A series of new alkyl 1-[N-(2-chloro-5-nitro-phenyl)-benzimidoyl] thioureas 3a-h were prepared from benzamides 1a-c. Benzimidoyl thioureas 3a-e afforded 5-nitro-2-phenyl-benzothiazole 5a-c under basic conditions via thiourea-isothiourea rearrangement and SNAr. A mechanistic rationalization supported by the direct formation of benzothioamide 8 and bis-benzimidoyl sulfide 9 derivatives from the reaction of imidoyl isothiocyanate 2 with bulky amines was supported.

Side chain polymers exhibiting nonlinear optical response

This invention provides novel side chain polymers which exhibit nonlinear optical response, and which have utility as a transparent optical component in all-optical and electrooptical light switch and light modulator devices. An invention side chain polymer is illustrated by the following structure: STR1