1372689-48-9Relevant academic research and scientific papers
Synthesis and characterization of copper(II) complexes of sulfadiazine with amino acids: Catalytic activity toward oxidation of phenol and catechol
Hanafy, Ahmed I.,El-Bahy, Zeinhom M.,Ali, Ibraheem O.
experimental part, p. 1459 - 1474 (2012/05/20)
New copper complexes of DL-methioninoylsulfadiazine (MTS) and L-cystinoylsulfadiazine (CYS) were prepared and characterized using elemental analysis, IR, electronic spectroscopy, EPR spectroscopy, and thermal analysis. The mode of binding indicates that copper binds to MTS through carbonyl oxygen with the amino group nitrogen while for CuII-CYS the copper binds through carbonyl oxygen and SH with removal of its proton. The proposed structures were supported by conformational analysis which showed predominance of the trans form of copper(II)-L-cystinoylsulfadiazine. The two complexes enhanced oxidation of phenol and catechol in the presence of H2O 2 under mild conditions. The catalyst shows proficiency toward oxidation of phenol and catechol compared to the auto-catalytic oxidation. CuII-MTS exhibited higher catalytic activity than Cu II-CYS. The phenol and catechol oxidation is inhibited by Kojic acid.
