1372783-84-0Relevant academic research and scientific papers
Process for preparing aromatic alkenyl compound (by machine translation)
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Paragraph 0078-0080; 0085, (2019/10/01)
The preparation method of the aromatic alkenyl compound comprises thioether and carbon-carbon double bond substrates, wherein the ratio of the amount of thioether to carbon-carbon double bond substrate is 1: (2 - 4), and [Cp * IrCl]. 2 ]2 And Cu (OAc)2 , Wherein [Cp * IrCl], is, for example. 2 ]2 Ratio (0.005 - 0.05): 1, Cu (OAc) to the amount of the thioether. 2 A ratio (1.2 - 2.4): 1, thioether, carbon-carbon double bond substrate, [Cp * IrCl]. 2 ]2 And Cu (OAc)2 The mixture, stirred 12h, in a solvent and the temperature of the reaction unitz 60 - 90 °C. The preparation method has the advantages of short reaction time consumption, wide selection range, no need of reaction under anaerobic, high pressure conditions, mild reaction conditions, less catalyst consumption; application to industrial production, saving of production cost, shortening of production cycle, good economical; targeted synthesis of a target product, and high controllability. (by machine translation)
Palladium-catalyzed C-H alkenylation of arenes using thioethers as directing groups
Yu, Ming,Xie, Yongju,Xie, Chunsong,Zhang, Yuhong
, p. 2164 - 2167 (2012/07/16)
Thioethers have been proven to be reliable directing groups for palladium catalyzed alkenylation of arenes via C-H activation. Mechanistic investigation reveals that the C-H cleavage of arenes is the turnover-limiting step, and an acetate-bridged dinuclear cyclopalladation intermediate is involved. The alkenylated thioethers can be easily removed and transformed into a variety of useful groups.
