137280-46-7Relevant academic research and scientific papers
Catalyst-free sulfenylation of indoles with sulfinic esters in ethanol
Yang, Xiuqin,Bao, Yishu,Dai, Zonghao,Zhou, Qingfa,Yang, Fulai
supporting information, p. 3727 - 3731 (2018/08/21)
A novel catalyst-free method for the synthesis of structurally diverse indole thioethers in moderate to excellent yields has been developed. In this reaction, sulfinic esters serve as new sulfur electrophiles.
Chiral N-Acyl-tert-butanesulfinamides: The "Safety-Catch" Principle Applied to Diastereoselective Enolate Alkylations
Backes, Bradley J.,Dragoli, Dean R.,Ellman, Jonathan A.
, p. 5472 - 5478 (2007/10/03)
Diastereoselective enolate alkylation reactions of N-acylsulfmamides and conversion of the alkylation products to a variety of enantiopure products are reported. Several sulfinamides were prepared in solution followed by acylation to provide N-acylsulfmamides. The N-acylsulfinamides were then evaluated in diastereoselective enolate alkylation reactions. Of the sulfinamides evaluated, tert-butanesulfinamide provided the highest diastereoselectivity. To establish the potential utility of sulfinamides as versatile auxiliaries, methods were developed for (1) the racemization-free acylation of tert-butanesulfinamide to prepare optically pure N-acyl-tert-butanesulfinamides, (2) the diastereoselective C-alkylation of N-acyl-tert-butanesulfmamides, (3) the conversion of the N-acyl-tert-butanesulfmamides to the active ester equivalent by N-alkylation and S-oxidation, and (4) the cleavage of the N-alkyl-N-acyl-tert-butanesulfonamides to give chiral alcohol, ester, amide, and carboxylic acid target compounds. These studies provide the groundwork for the development of sulfinamides as dual chiral auxiliaries and linkers for the multistep solid-phase synthesis of enantioenriched compounds.
NMR of Terminal Oxygen, 6 - 17O NMR of the S-O 'Double Bond': Derivatives of Arylsulphinic and Arylsulphonic Acids
Dahn, Hans,Toan, Vien Van,Ung-Truong, My-Ngoc
, p. 897 - 903 (2007/10/02)
The 17O NMR spectra of terminal oxygen atoms in esters, anions and amides of substituted arenesulphinic acids and in esters and amides of substituted arenesulphonic acids were measured.The signals of the terminal O appear close to those of the bridge O.Co
