59057-35-1

Basic information

• Product Name: 2,4,6-trimethylbenzenesulfinic acid
• CAS NO: 59057-35-1
• Molecular Formula: C₉H₁₂O₂S
• Molecular Weight: 184.2554
• Mol File: 59057-35-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 363.4°C at 760 mmHg
• Flash Point: 173.6°C
• Density: 1.26g/cm³
• Vapor Pressure: 6.45E-06mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 2,4,6-trimethylbenzenesulfinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-trimethylbenzenesulfinic acid(59057-35-1)
• EPA Substance Registry System: 2,4,6-trimethylbenzenesulfinic acid(59057-35-1)

Safety Data

• Hazardous Substances Data: 59057-35-1(Hazardous Substances Data)

Usage

General Description

2,4,6-trimethylbenzenesulfinic acid, also known as mesitylene sulfinic acid, is a chemical compound with the molecular formula C9H10O2S. It is a colorless to light yellow solid with a sulfurous odor and is used as a chemical intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also used as a reducing agent in organic and bioorganic chemistry. Additionally, it is a versatile reagent for the conversion of carbonyl compounds to their corresponding oximes, which are important intermediates in the synthesis of various pharmaceuticals and fine chemicals. Mesitylene sulfinic acid is also utilized in the manufacture of polymers and as a source of sulfur dioxide in some organic reactions.

Upstream product

• 71-43-2 benzene 
• 82965-02-4 hexyl 2,4,6-trimethylbenzenesulfonate 
• 3112-79-6 dimesityl sulfone 
• 108-67-8 1,3,5-trimethyl-benzene 
• 773-64-8 2-mesitylenesulphonyl chloride 

Downstream Products

• 59057-28-2 Acetic acid (2E,6E,8E)-3,7-dimethyl-5-(2,4,6-trimethyl-benzenesulfonyl)-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,6,8-trienyl ester 
• 73766-66-2 S_S-l-menthyl 2,4,6-trimethylbenzenesulfinate 
• 73766-51-5 R_S-l-menthyl 2,4,6-trimethylbenzenesulfinate 
• 73766-54-8 (+)-(R)-(1-Cyclohexenylmethyl)-mesityl-sulfoxid 
• 73766-53-7 (-)-(R)-(Cyclohexylidenmethyl)-mesityl-sulfoxid 
• 253316-09-5 (RS)-N-[carbo-(1R)-menthoxy]-2,4,6-trimethylbenzenesulfonimidoyl chloride 
• 137280-44-5 methyl 2,4,6-trimethylbenzenesulphinate 
• 137280-46-7 ethyl 2,4,6-trimethylbenzenesulphinate 
• 73766-65-1 2,4,6-trimethylbenzenesulfinyl chloride 
• 1483-92-7 bis(2,4,6-trimethylphenyl)disulfide 
• 135216-98-7 2,4,6-trimethylphenyl 1-methyl-4-nitro-5-imidazolyl sulfone 
• 59057-21-5 1,3,5-Trimethyl-2-[(2E,4E)-3-methyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-penta-2,4-diene-1-sulfonyl]-benzene 
• 39153-60-1 S-mesityl 2,4,6-trimethylbenzenesulfonothioate 
• 6462-31-3 methyl 2,4,6-trimethylphenyl sulfone 

Relevant articles and documents

Palladium-catalyzed desulfitative heck-type reaction of aryl sulfinic acids with alkenes

An efficient protocol has been developed for the desulfitative Heck-type reaction of aryl sulfinic acids with a variety of alkenes in the presence of a catalytic amount of Pd(OAc)2 and inexpensive Cu(OAc)2 as oxidant. This method does not require a ligand or a base, thereby broadening the scope of Pd-catalyzed coupling reactions. Copyright

STUDIEN ZUM VORGANG DER WASSERSTOFFUEBERTRAGUNG 64. ELECTROREDUCTIVE SPALTUNG VON ARYLSULFONSAEUREDERIVATEN UND ARYLSULFONEN MIT ALKALI-AMALGAMEN

Arylsulfonylchlorides, n-hexylarylsulfonates and di-aryl sulfones (ArSO2Y; Y=Cl, OC6H13, Ar') were cleaved under standard conditions by alkali metal amalgams (M/Hg; M=Li, Na, K) to the corresponding sulfinate salts (ArSO2M) and MY, as shown in Eq. 1.The substrates ArSO2Y in toluene were not cleaved by Li/Hg alone; first on addition of an equimolar amount of i-propanol could conversions of almost 100percent be achieved. (Tables I,II,III).A series of six n-hexylarylsulfonates were studied under standard conditions, to establish the influence of the reaction medium and the amalgam on the course of reaction, (Table II).The sterically hindered arylsulfonates ArSO2OC6H13, (Ar= mesityl, 2,4,6-tri-isopropyl) were "anomalous", i.e. underwent fission at the ring/sulfur bond , as shown by Eq. 2.Table III describes the reductive fission of mesityl-phenylsulfone and dimesitylsulfone.