1372804-72-2Relevant academic research and scientific papers
The acid-mediated ring opening reactions of α-aryl-lactams
King, Frank D.,Caddick, Stephen
supporting information; experimental part, p. 3244 - 3252 (2012/06/01)
4-Aryl-azetidin-2-ones (β-lactams) undergo ring opening with triflic acid to give cinnamamides which, in benzene, react further to give 3-aryl-3-phenyl-propionamides. Prolonged reaction times in benzene give 3,3-diphenyl-propionamide via an aryl/phenyl ex
